Zestril, or Lisinopril, is one of a class of drugs known as ACE Inhibitors. When used as an antihypertensive, Zestril helps lower high blood pressure by blocking an enzyme that causes the tightening of blood vessels.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as use during pregnancy can cause low blood pressure, severe kidney failure, too much potassium, or even the death of your baby.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor if you have any signs of infection (chills, fever, or sore throat), or have severe or continuing diarrhea, or notice any signs of jaundice (yellowing of skin or eyes). Be especially careful during exercise or hot weather. Get immediate medical attention if you experience any welts or swelling around your face, throat or tongue.
Lisinopril is an oral long-acting angiotensin converting enzyme inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-carboxy-3-phenylpropyl) -L-lysyl]-L-proline dihydrate. Its empirical formula is C21H31N3O5.2H2O. ZESTRIL is supplied as 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg and 40 mg tablets for oral administration.
2.5 mg tablets - calcium phosphate, magnesium stearate, mannitol, starch.
5, 10, 20 and 30 mg tablets - calcium phosphate, magnesium stearate, mannitol, red ferric oxide, starch.
40 mg tablets - calcium phosphate, magnesium stearate, mannitol, starch, yellow ferric oxide.
Zestril has the following structural formula:
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