Cyanocobalamin is a synthetic or man-made form of vitamin B12. Vitamin B12, one of the B-complex vitamins is important for growth, cell reproduction, blood formation, and protein and tissue synthesis. Cyanocobalamin is used to treat pernicious anemia, nutritional vitamin B12 deficiency, malabsorption of vitamin B12, and other cases of vitamin B12 deficiency.
It is important that you have to use this medication regularly and for lifetime if you have pernicious anemia otherwise an irreversible damage to the nerves and spinal cord can occur. Also, folic acid therapy cannot be substituted for cyanocobalamin. Folic acid may prevent megaloblastic anemia which is a macrocytic type of anemia similar to pernicious anemia but it will allow progressive damage to the spinal cord.
Before taking this medication, tell your doctor if you have Leber's disease. People with this condition and taking Cyanocobalamin may develop optic nerve damage and possibly blindness. Cyanocobalamin is not known whether it will harm an unborn baby. However, vitamin B12 is important to the proper development of a baby. Talk to your doctor about this medication if you are pregnant. Cyanocobalamin passes into breast milk but it is necessary for both mother and child during breast-feeding.
Take cyanocobalamin as directed by your doctor. Oral tablets with a full glass of water,
the injectable form is usually injected into the muscle or just beneath the skin monthly with specific instructions from your doctor and the nasal gel (usually one dose in one nostril) once a week to treat pernicious anemia. If you are using the nasal spray, tell your doctor if you develop nasal congestion, a cold, or allergies. The nasal spray may not work as well if you are congested.
Symptoms of cyanocobalamin overdose are not known and overdose of this medicine is unlikely to be life threatening. Call your doctor, an emergency room, or a poison control left for advice if you suspect an overdose.
Serious side effects that necessitates emergency medical attention : an allergic reaction (difficulty breathing; closing of your throat; swelling of lips, tongue, or face; or hives);
chest pain or difficulty breathing; or unusual warmth, redness, or pain in an arm or leg.
You may continue taking cyanocobolamin but inform your doctor if you experience these less serious side effects : headache; upset stomach or diarrhea; numbness or tingling;
fever; dizziness; felling of swelling of entire body; or itching or rash. Talk to your doctor about any other unusual side effects.
Do not use any other nasal medications while using cyanocobalamin nasal unless they are approved by your doctor. Use the nasal spray one hour before or after eating or drinking hot foods or liquids.
Possible drug interactions may happen if you are taking any of the following medications: antibiotics, methotrexate (Rheumatrex), or pyrimethamine (Daraprim). These medicines may interfere with diagnostic tests for vitamin B12 and folic acid.
Also, colchicines or heavy alcohol use for 2 weeks or longer can cause decreased cyanocobalamin absorption. To be safe, inform your doctor and pharmacist before taking any prescription or over-the-counter medicines.
The chemical name is 5,6-dimethyl-benzimidazolyl cyanocobamide; the molecular formula is C63H88CON14O14P. The cobalt content is 4.34%. The molecular weight is 1355.39. Each vial also contains sodium chloride, 0.9%. Benzyl alcohol, 1.5%, is present as a preservative. Sodium hydroxide and/or hydrochloric acid may have been added during manufacture to adjust the pH (range 4.5-7.0). Cyanocobalamin Injection, USP is a sterile solution of cyanocobalamin for intramuscular or subcutaneous injection. Each mL contains 1,000 mcg cyanocobalamin.
Vitamin B12 has the following structural formula:
Generic name: Cyanocobalamin
Brand name(s): B 12 Resin :: Cobal 1000 :: Crystal B 12 :: Crystamine :: Crysti 12 :: Cyanoject :: Cyomin :: LA 12 :: Neuroforte R :: Sytobex :: Vibal
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