Toprol is one of a group of medicines known as beta-adrenergic blocking agents, beta-blocking agents, or, most frequently, beta-blockers. Beta-blockers are used in the treatment of high blood pressure, and some are used to relieve chest pain and in heart attack, patients to help prevent additional heart attacks. Beta-blockers are also used to correct an irregular heartbeat, prevent migraine headaches, and treat tremors.
Beta-blockers work by changing the response to nerve impulses in certain parts of the body. As a result, they decrease the heart's need for blood and oxygen by reducing its workload and help the heart to beat more regularly.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Toprol may affect your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and never stop taking Toprol without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Tell your doctor as soon as possible if any of the following side effects occur: breathing difficulty and/or wheezing; cold hands and feet; mental depression; shortness of breath; slow heartbeat; swelling of ankles, feet, and/or lower legs; back pain or joint pain; chest pain; confusion; dizziness or lightheadedness when getting up from a lying or sitting position; fever and sore throat; hallucinations; irregular heartbeat; red, scaling, or crusted skin; skin rash; or unusual bleeding and bruising.
Toprol-XL, metoprolol succinate, is a beta1-selective (cardioselective) adrenoceptor blocking agent, for oral administration, available as extended release tablets. Toprol-XL has been formulated to provide a controlled and predictable release of metoprolol for once daily administration. The tablets comprise a multiple unit system containing metoprolol succinate in a multitude of controlled release pellets. Each pellet acts as a separate drug delivery unit and is designed to deliver metoprolol continuously over the dosage interval. The tablets contain 47.5 mg, 95 mg and 190 mg of metoprolol succinate equivalent to 50, 100 and 200 mg of metoprolol tartrate, USP, respectively. Its chemical name is (±) 1-(isopropylamino)-3-[p-(2-methoxyethyl) phenoxy]-2-propanol succinate (2:1) (salt).
Toprol has the following structural formula: