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    Tolterodine
Tolterodine pill Tolterodine review
by
Pharmacy and Drugs


     .: Prescription

Tolterodine relieves spasms of the bladder. It is used to treat overactive bladder with the symptoms of urinary frequency, urinary urgency, and urinary incontinence. Tolterodine may also be used for purposes other than those listed in this medication guide.

Take tolterodine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Do not crush, chew, or open the long-acting capsules (Detrol LA). Swallow them whole. They are specially formulated to slowly release the medication in your body. Do not take more of this medication than is prescribed for you. If your symptoms are not being treated, notify your doctor. Store tolterodine at room temperature away from moisture and heat.

If you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), stop taking tolterodine and seek emergency medical attention. Other, less serious side effects may be more likely to occur. Continue to take tolterodine and talk to your doctor if you experience: dry mouth, dryness of the eyes, blurred vision or large pupils, upset stomach, headache, constipation, difficulty urinating, drowsiness, or dizziness. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Use caution when driving, operating machinery, or performing other hazardous activities. Tolterodine may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking tolterodine. Avoid becoming overheated in hot weather. Tolterodine may increase the risk of heat stroke because it may decrease sweating. Drink plenty of fluid to maintain adequate hydration.

Symptoms of a tolterodine overdose are not known but might include restlessness, tremor, irritability, seizures, delirium, hallucinations, flushing, fever, nausea, vomiting, a fast heartbeat, and possibly coma.

Before taking tolterodine, tell your doctor if you are taking any of the following medicines: clarithromycin (Biaxin) or erythromycin (E-Mycin, Ery-Tab, E.E.S., P.C.E., others); ketoconazole (Nizoral), itraconazole (Sporanox), or miconazole (Monistat); cyclosporine (Neoral, Sandimmune); or vinblastine (Velban).

You may need a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Tolterodine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.

Drugs other than those listed here may also interact with tolterodine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Tolterodine Capsules contain tolterodine tartrate. The active moiety, tolterodine, is a muscarinic receptor antagonist. The chemical name of tolterodine tartrate is (R)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl) -3-phenylpropanamine L-hydrogen tartrate. The empirical formula of tolterodine tartrate is C26H37NO7, and its molecular weight is 475.6. Tolterodine for oral administration contains 2 mg or 4 mg of tolterodine tartrate. Inactive ingredients are sucrose, starch, hypromellose, ethylcellulose, medium chain triglycerides, oleic acid, gelatin, and FD&C Blue #2. The 2-mg capsules also contain yellow iron oxide. Both capsule strengths are imprinted with a pharmaceutical grade printing ink that contains shellac glaze, titanium dioxide, propylene glycol, and simethicone.

Tolterodine has the following structural formula:

Chemical structure of Tolterodine
Brand name: Detrol :: Detrol LA

Similar drugs: Furosemide :: Ampicillin :: Cephalexin

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