Tobradex, or Tobramycin and Dexamethasone, is a combination of an antibiotic and a corticosteroid used in the eye to prevent permanent damage, which may occur with certain eye problems.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Tobradex may affect your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Talk with your doctor as soon as possible if any of the following side effects occur: itching and swelling of eyelid; redness of the eye; delayed wound healing; eye pain; or gradual blurring or loss of vision.
Tobramycin: Empirical Formula: C18H37N5O9
Chemical Name: O-3-Amino-3-deoxy-a-D-glucopyranosyl- (1“4)-O-[2,6-diamino-2,3,6-trideoxy-a-D-ribo-hexopyransol- (1“6)]-2-deoxy-L-streptamine.
Dexamethasone: Empirical Formula: C22H29FO5
Chemical Name: 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-dien-3,20-dione.
Each ml of Tobradex Suspension Contains: Actives: Tobramycin 0.3% (3 mg) and dexamethasone 0.1% (1 mg). Preservative: Benzalkonium chloride 0.01%. Inactives: Tyloxapol, edetate disodium, sodium chloride, hydroxyethyl cellulose, sodium sulfate, sulfuric acid and/or sodium hydroxide (to adjust pH) and purified water.
Each Gram of Tobradex Ointment Contains: Actives: Tobramycin 0.3% (3 mg) and dexamethasone 0.1% (1 mg). Preservative: Chlorobutanol 0.5%. Inactives: Mineral Oil and White Petrolatum.
Tobradex has the following structural formula:
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