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    Tamoxifen Citrate
Tamoxifen tablets Tamoxifen Citrate review
by
Pharmacy and Drugs


     .: Prescription

Tamoxifen Citrate is a medicine that blocks the effects of in the body. It is usually used to treat breast cancer in women or men, but may also be used to treat other kinds of cancer. Tamoxifen Citrate may also be used to reduce the risk of developing breast cancer in women who have a high risk. Women at high risk for developing breast cancer are at least 35 years old and have a combination of risk factors that make their chance of developing breast cancer 1.67% or more over the next 5 years. Your doctor will help to determine your risk of developing breast cancer.

Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Tamoxifen Citrate may affect your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.

It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.

Tell your doctor as soon as possible if any of the following side effects occur: (for both females and males) anxiety; blistering, peeling, or loosening of skin and mucous membranes; blurred vision; chest pain; confusion; cough; dizziness; fainting; fast heartbeat; lightheadedness; pain or swelling in legs; shortness of breath or trouble breathing; weakness or sleepiness; or yellow eyes or skin.

(For females only) change in vaginal discharge; chills; fever; hoarseness; lower back or side pain; pain or feeling of pressure in pelvis; pain, redness, or swelling in your arm or leg; painful or difficult urination; rapid shallow breathing; skin rash or itching over the entire body; sweating; vaginal bleeding; or wheezing.

NOLVADEX(tamoxifen citrate) Tablets, a nonsteroidal antiestrogen, are for oral administration. NOLVADEX Tablets are available as: 10 mg Tablets: Each tablet contains 15.2 mg of tamoxifen citrate which is equivalent to 10 mg of tamoxifen.
20 mg Tablets: Each tablet contains 30.4 mg of tamoxifen citrate which is equivalent to 20 mg of tamoxifen.
Chemically, NOLVADEX is the trans-isomer of a triphenylethylene derivative. The chemical name is (Z)2-[4- (1,2-diphenyl-1-butenyl) phenoxy]-N, N-dimethylethanamine 2 hydroxy-1,2,3- propanetricarboxylate (1:1). Tamoxifen citrate has a molecular weight of 563.62, the pKa’ is 8.85, the equilibrium solubility in water at 37C is 0.5 mg/mL and in 0.02 N HCl at 37C, it is 0.2 mg/mL.

Tamoxifen Citrate has the following structural formula:

Chemical structure of 
Tamoxifen Citrate
Brand name: Nolvadex

Similar drugs: Letrozole :: Anastrozole :: Femara

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