|
What is the most important information I should know about tadalafil?
|
|
• |
Do not take tadalafil if you are also using a nitrate drug
for chest pain or heart problems. This includes nitroglycerin (Nitrostat,
Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR,
Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket).
Nitrates are also found in some recreational drugs such as amyl nitrate
or nitrite ("poppers"). Taking tadalafil with a nitrate medicine can
cause a serious decrease in blood pressure, leading to fainting, stroke,
or heart attack. |
|
• |
If you become dizzy or nauseated, or have pain, numbness, or
tingling in your chest, arms, neck, or jaw during sexual activity, stop
and call your doctor right away. You could be having a serious side
effect of tadalafil. |
|
• |
Do not take tadalafil more than once a day. Allow 24 hours to
pass between doses. |
|
• |
Contact your doctor or seek emergency medical attention if
your erection is painful or lasts longer than 4 hours. A prolonged
erection (priapism) can damage the penis. |
|
• |
A small number of patients have had a sudden loss of eyesight
after taking tadalafil. This type of vision loss is caused by decreased
blood flow to the optic nerve of the eye. It is not clear whether
tadalafil is the actual cause of such vision loss. Sudden vision loss
with tadalafil use has occurred most often in people with heart disease,
diabetes, high blood pressure, high cholesterol, or certain pre-existing
eye problems, and in those who smoke or are over 50 years old. |
|
• |
Stop using tadalafil and get emergency medical help if you
have sudden vision loss. |
|
• |
Tadalafil relaxes muscles and increases blood flow to
particular areas of the body. |
|
• |
Tadalafil is used to treat erectile dysfunction (impotence). |
|
• |
Tadalafil may also be used for purposes other than those
listed in this medication guide. |
|
What should I discuss with my healthcare provider before taking
tadalafil?
|
|
• |
Do not take tadalafil if you are also using a nitrate drug
for chest pain or heart problems. This includes nitroglycerin (Nitrostat,
Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR,
Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket).
Nitrates are also found in some recreational drugs such as amyl nitrate
or nitrite ("poppers"). Taking tadalafil with a nitrate medicine can
cause a serious decrease in blood pressure, leading to fainting, stroke,
or heart attack. |
|
• |
A small number of patients have had a sudden loss of
eyesight after taking tadalafil. This type of vision loss is caused by
decreased blood flow to the optic nerve of the eye. It is not clear
whether tadalafil is the actual cause of such vision loss. Sudden vision
loss with tadalafil use has occurred most often in people with heart
disease, diabetes, high blood pressure, high cholesterol, or certain
pre-existing eye problems, and in those who smoke or are over 50 years
old. |
|
• |
Before taking tadalafil, tell your doctor if you have: |
| |
· |
heart disease or heart rhythm problems; |
| |
· |
a recent history a heart attack (within the past 90 days); |
| |
· |
a recent history of stroke or congestive heart failure (within
the past 6 months); |
| |
· |
high or low blood pressure; |
| |
· |
kidney disease (or if you are on dialysis); |
| |
· |
a blood cell disorder such as sickle cell anemia, multiple
myeloma, or leukemia; |
| |
· |
a bleeding disorder such as hemophilia; |
| |
· |
retinitis pigmentosa (an inherited condition of the eye); |
| |
· |
a physical deformity of the penis (such as Peyronie's
disease); or |
| |
· |
if you have been told you should not have sexual intercourse
for health reasons. |
|
• |
If you have any of these conditions, you may not be able to
use tadalafil or you may need a dosage adjustment or special tests
during treatment. |
|
• |
FDA pregnancy category B: Although tadalafil is not for use
in women, this medication is not expected to be harmful to an unborn
baby. Do not use tadalafil without telling your doctor if you are
pregnant or plan to become pregnant during treatment. |
|
• |
Although tadalafil is not for use in women, it is not known
if tadalafil passes into breast milk or if it could harm a nursing baby.
Do not use this medication without telling your doctor if you are
breast-feeding a baby. |
|
• |
You may need a lower dose of this medication if you are
older than 65. Follow your doctor's instructions. |
|
How should I take tadalafil?
|
|
• |
Take tadalafil exactly as it was prescribed for you. Do not
take it in larger doses or for longer than recommended by your doctor. |
|
• |
Take each dose with a full glass of water. |
|
• |
Tadalafil can be taken with or without food. |
|
• |
Tadalafil is usually taken only when needed, just before
sexual activity. The medication can help achieve an erection when sexual
stimulation occurs. An erection will not occur just by taking a pill.
Follow your doctor's instructions. |
|
• |
Do not take tadalafil more than once a day. Allow 24 hours
to pass between doses. |
|
• |
Contact your doctor or seek emergency medical attention if
your erection is painful or lasts longer than 4 hours. A prolonged
erection (priapism) can damage the penis. |
|
• |
Store this medication at room temperature away from moisture
and heat. |
|
What happens if I miss a dose?
|
|
• |
Since tadalafil is used as needed, you are not likely to be
on a dosing schedule. |
|
What happens if I overdose?
|
|
• |
Seek emergency medical attention if you think you have used
too much of this medicine. |
|
• |
Symptoms of a tadalafil overdose may include chest pain,
nausea, irregular heartbeat, and feeling light-headed or fainting. |
|
What should I avoid while taking tadalafil?
|
|
• |
Avoid drinking alcohol, which can increase some of the side
effects of tadalafil. |
|
• |
Grapefruit and grapefruit juice may interact with tadalafil.
Discuss the use of grapefruit products with your doctor. Do not increase
or decrease the amount of grapefruit products in your diet without first
talking to your doctor. |
|
• |
Do not use any other drug to treat impotence, such as
alprostadil (Caverject, Muse, Edex) or yohimbine (Yocon, Yodoxin, others),
unless your doctor tells you to. |
|
What are the possible side effects of tadalafil?
|
|
• |
If you become dizzy or nauseated, or have pain, numbness, or
tingling in your chest, arms, neck, or jaw during sexual activity, stop
and call your doctor right away. You could be having a serious side
effect of tadalafil. |
|
• |
Stop using tadalafil and get emergency medical help if you
have sudden vision loss. |
|
• |
Get emergency medical help if you have any of these signs
of an allergic reaction: hives; difficulty breathing; swelling of
your face, lips, tongue, or throat. |
|
• |
Stop using tadalafil and call your doctor at once if you
have any of these serious side effects: |
| |
· |
chest pain or heavy feeling, pain spreading to the arm or
shoulder, nausea, sweating, general ill feeling; |
| |
· |
swelling in your hands, ankles, or feet; |
| |
· |
feeling light-headed, fainting; or |
| |
· |
penis erection that is painful or lasts 4 hours or longer. |
|
• |
Continue taking tadalafil and talk with your doctor if you have any
of these less serious side effects: |
| |
· |
warmth or redness in your face, neck, or chest; |
|
• |
Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
|
What other drugs will affect tadalafil?
|
|
• |
Before taking tadalafil, tell your doctor if you are using any of
the following medications: |
| |
· |
cimetidine (Tagamet, Tagamet HB); |
| |
· |
erythromycin (E-Mycin, Eryc, Ery-Tab) or clarithromycin (Biaxin); |
| |
· |
doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin); |
| |
· |
HIV medicines such as amprenavir (Agenerase), tipranavir (Aptivus),
darunavir (Prezista), efavirenz (Sustiva), nevirapine (Viramune),
indinavir (Crixivan), saquinavir (Invirase, Fortovase), lopinavir/
ritonavir (Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir),
atazanavir (Reyataz), or nelfinavir (Viracept); |
| |
· |
itraconazole (Sporanox) or ketoconazole (Nizoral); |
| |
· |
carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin);
or |
| |
· |
rifampin (Rifadin, Rimactane). |
|
• |
If you are using any of these drugs, you may not be able to take
tadalafil, or you may need dosage adjustments or special tests during
treatment. |
|
• |
There may be other drugs not listed that can affect tadalafil. Tell
your doctor about all the prescription and over-the-counter medications
you use. This includes vitamins, minerals, herbal products, and drugs
prescribed by other doctors. Do not start using a new medication without
telling your doctor. |
|
Where can I get more information?
|
|
• |
Your pharmacist has additional information about tadalafil written
for health professionals that you may read. |
|
• |
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
|
• |
Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.02. Revision date: 7/
10/ 06. |