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What is the most important information I should know about
sumatriptan injection?
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Sumatriptan can cause serious side effects on the heart,
including heart attack or stroke. Although these side effects are rare,
do not use this medication if you have a history of heart disease,
angina (chest pain), blood circulation problems, ischemic bowel disease,
severe or uncontrolled high blood pressure, or history of a heart attack
or stroke. |
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Before using sumatriptan, tell your doctor if you have a
seizure disorder, coronary artery disease, or risk factors for coronary
artery disease (such as diabetes, menopause, smoking, being overweight,
having high blood pressure or high cholesterol, having a family history
of coronary artery disease, being older than 40 and a man, or being a
woman who has had a hysterectomy). |
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Do not use sumatriptan if you have taken a monoamine oxidase
inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate),
rasagiline (Azilect), selegiline (Eldepryl, Emsam), or phenelzine (Nardil)
in the past 14 days. |
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Sumatriptan injection is used to treat migraine headaches and
cluster headaches. Sumatriptan will only treat a headache that
has already begun. It will not prevent headaches or reduce the
number of attacks. |
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Do not use sumatriptan within 24 hours after taking
almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova),
rizatriptan (Maxalt), naratriptan (Amerge), zolmitriptan (Zomig), or
ergot medicine such as methysergide (Sansert), ergotamine (Ergomar,
Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45,
Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine). |
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Before using sumatriptan, tell your doctor if you are also
taking an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta),
escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox),
paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor). |
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After using a sumatriptan injection, you must wait one hour
before using a second injection. Do not use more than two injections
in 24 hours. |
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What is sumatriptan injection?
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Sumatriptan is a headache medicine. It is believed to work
by narrowing the blood vessels around the brain. Sumatriptan also
reduces substances in the body that can trigger headache pain, nausea,
sensitivity to light and sound, and other migraine symptoms. |
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Sumatriptan injection is used to treat migraine headaches
and cluster headaches. |
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Sumatriptan will only treat a headache that has
already begun. It will not prevent headaches or reduce the number
of attacks. |
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Sumatriptan may also be used for purposes other than those
listed in this medication guide. |
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What should I discuss with my health care provider before using
sumatriptan injection?
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Do not use this medication if you are allergic to
sumatriptan, or if you have: |
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a history of heart disease, angina (chest pain), blood
circulation problems, or history of a heart attack or stroke; |
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ischemic bowel disease; |
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severe or uncontrolled high blood pressure; or |
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Do not use sumatriptan if you have taken a monoamine oxidase
inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate),
rasagiline (Azilect), selegiline (Eldepryl, Emsam), or phenelzine (Nardil)
in the past 14 days. |
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Do not use sumatriptan within 24 hours after taking
any of the following medicines: |
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almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova),
naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan
(Zomig); or |
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ergot medicine such as methysergide (Sansert), ergotamine (Ergomar,
Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45,
Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine). |
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Before using sumatriptan, tell your doctor if you have: |
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epilepsy or other seizure disorder; |
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coronary artery disease (or risk factors that include
diabetes, menopause, smoking, being overweight, having high blood
pressure or high cholesterol, having a family history of coronary artery
disease, being older than 40 and a man, or being a woman who has had a
hysterectomy). |
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If you have any of these conditions, you may not be able to
use sumatriptan, or you may need a dosage adjustment or special tests
during treatment. |
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FDA pregnancy category C. This medication may be harmful to
an unborn baby. Tell your doctor if you are pregnant or plan to become
pregnant during treatment. |
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Your name may need to be listed on a sumatriptan pregnancy
registry when you start using this medication. |
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Sumatriptan can pass into breast milk and may harm a nursing
baby. Do not use this medication without telling your doctor if you are
breast-feeding a baby. |
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This medicine should not be given to anyone under 18 or over
65 years of age. |
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How should I use sumatriptan injection?
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Use this medication exactly as it was prescribed for you. Do
not use the medication in larger or smaller amounts, or use it for
longer than recommended by your doctor. Follow the instructions on your
prescription label. |
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Use sumatriptan as soon as you notice headache symptoms, or
after an attack has already begun. |
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Your doctor may want to give your first dose of this
medicine in a hospital or clinic setting to see if you have any serious
side effects. |
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Sumatriptan injection comes in a prefilled cartridge to be
loaded into an autoinjector syringe. Each cartridge contains only one
dose that you will inject into your skin. This medicine comes with
patient instructions for injecting it. Do not give yourself an injection
if you do not understand these instructions. Ask your doctor or
pharmacist if you have questions. |
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After using an injection: If your headache does not
completely go away after the injection, call your doctor before using a
second sumatriptan injection. If your headache goes away and then comes
back, you may use a second injection if it has been at least one hour
since your first injection. Do not use more than two injections in 24
hours. If your symptoms do not improve, contact your doctor before
using any more injections. |
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Contact your doctor if you have more than four headaches in
one month (30 days). |
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Store this medicine at room temperature away from moisture,
heat, and light. |
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What happens if I miss a dose?
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Since sumatriptan is used as needed, it does not have a
daily dosing schedule. After using a sumatriptan injection, you must
wait one hour before using a second injection. Do not use more than
two injections in 24 hours. |
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What happens if I overdose?
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Seek emergency medical attention if you think you have used
too much of this medicine, or if anyone else has accidentally injected
it. |
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Symptoms of a sumatriptan overdose may include seizure (convulsions),
tremors or shaking, skin redness, breathing problems, blue-colored lips
or fingernails, vision problems, watery eyes or mouth, and weakness or
lack of coordination. |
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What should I avoid while using sumatriptan injection?
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Sumatriptan can cause side effects that may impair your
thinking or reactions. Be careful if you drive or do anything that
requires you to be awake and alert. |
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What are the possible side effects of sumatriptan injection?
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Get emergency medical help if you have any of these signs
of an allergic reaction: hives; difficulty breathing; swelling of
your face, lips, tongue, or throat. |
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Stop using sumatriptan and call your doctor at once if you
have any of these serious side effects: |
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chest pain or heavy feeling, pain spreading to the arm or
shoulder, nausea, sweating, general ill feeling; |
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sudden numbness or weakness, especially on one side of the
body; |
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sudden headache, confusion, problems with vision, speech, or
balance; |
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fast heart rate, agitation, muscle stiffness, hallucinations,
lack of coordination, with nausea, vomiting, or diarrhea; |
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sudden and severe stomach pain and bloody diarrhea; |
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seizure (convulsions); or |
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numbness or tingling and a pale or blue-colored appearance
in your fingers or toes. |
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Continue using sumatriptan and talk with your doctor if you
have any of these less serious side effects: |
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nausea, vomiting, diarrhea; |
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warmth or redness under your skin; |
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pressure or heavy feeling in any part of your body; |
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sneezing, runny nose, congestion, cough; |
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pain or redness where you injected the medicine; |
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feeling dizzy or sleepy; or |
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Side effects other than those listed here may also occur.
Talk to your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect sumatriptan injection?
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Before using sumatriptan, tell your doctor if you are using
any of the following drugs: |
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an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta),
escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox),
paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor); or |
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another migraine medicine such as almotriptan (Axert),
eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge),
rizatriptan (Maxalt), or zolmitriptan (Zomig). |
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If you are using any of these drugs, you may not be able to use
sumatriptan, or you may need dosage adjustments or special tests during
treatment. |
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There may be other drugs not listed that can affect sumatriptan.
Tell your doctor about all the prescription and over-the-counter
medications you use. This includes vitamins, minerals, herbal products,
and drugs prescribed by other doctors. Do not start using a new
medication without telling your doctor. |
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Where can I get more information?
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Your pharmacist has more information about sumatriptan written for
health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed |
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Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.03. Revision date: 8/
10/ 06. |