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    Sumatriptan
Sumatriptan pill Sumatriptan review
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Pharmacy and Drugs


     .: Prescription

Sumatriptan is a headache medicine and works by narrowing the blood vessels around the brain. It also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. Sumatriptan injection is used to treat migraine and cluster headaches. However, it will only treat a headache that has already begun but does not prevent headaches or reduce the number of migraine attacks.

Do not use this medication if you are allergic to sumatriptan, or if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or phenelzine (Nardil) in the past 14 days.

Do not use sumatriptan within 24 hours after taking any of the following medicines: almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig); or ergot medicine such as methysergide (Sansert), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine).

Before using sumatriptan, tell your doctor if you have: epilepsy or other seizure disorder; blood circulation problems, or history of a heart attack or stroke; ischemic bowel disease; high blood pressure; liver disease; kidney disease; or coronary artery disease (or risk factors that include diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

This medication may be harmful to an unborn baby. It can also pass into breast milk hence, may affect a nursing baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Sumatriptan should not be given to anyone under 18 or over 65 years of age. Sumatriptan may impair your thinking or reactions so be careful if you drive or do anything that requires you to be awake and alert.

If your headache does not completely go away after a sumatriptan injection, call your doctor before using a second sumatriptan injection. If your headache goes away and then comes back, you may use a second injection if it has been at least one hour since your first injection as long as you must not use more than two injections in 24 hours. If your symptoms do not improve or if you have more than four headaches in one month (30 days) contact your doctor before using any more injections.

Seek emergency medical attention if you think you have used too much of this medicine, or if anyone else has accidentally injected it. Symptoms of a sumatriptan overdose may include seizure (convulsions), tremors or shaking, skin redness, breathing problems, blue-colored lips or fingernails, vision problems, watery eyes or mouth, and weakness or lack of coordination.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Discontinue using sumatriptan if you have any of the following serious side effects: chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; sudden numbness or weakness, especially on one side of the body; sudden headache, confusion, problems with vision, speech, or balance; fast heart rate, agitation, muscle stiffness, hallucinations, lack of coordination, with nausea, vomiting, or diarrhea; sudden and severe stomach pain and bloody diarrhea; seizure (convulsions); or numbness or tingling and a pale or blue-colored appearance in your fingers or toes.

You may continue using sumatriptan but discuss to your doctor if you have any of these less serious side effects: nausea, vomiting, diarrhea; muscle pain; warmth or redness under your skin; pressure or heavy feeling in any part of your body; sneezing, runny nose, congestion, cough; pain or redness where you injected the medicine; feeling dizzy or sleepy; or drooling or sweating. Talk to your doctor about any other unusual side effect.

Drug interactions may occur if you are using any of the following drugs with sumatriptan: an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), or venlafaxine (Effexor); or another migraine medicine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig).

Discuss to your doctor about all the prescription and over-the-counter medications you use including vitamins, minerals, herbal products, and drugs prescribed by other doctors.

The empirical formula is C14H21N3O2S·C4H6O4, representing a molecular weight of 413.5. Sumatriptan succinate is a white to off-white powder that is readily soluble in water and in saline. Each Imitrex tablet for oral administration contains 35 or 70 mg of sumatriptan succinate equivalent to 25 or 50 mg of sumatriptan, respectively. Each tablet also contains the inactive ingredients croscarmellose sodium, lactose, magnesium stearate, microcrystalline cellulose, and titanium dioxide dye.

Sumatriptan has the following structural formula:

Chemical structure of Sumatriptan
Brand name: Imitrex :: Imitrex Statdose

Similar drugs: Cyclobenzaprine :: Vicoprofen :: Atenolol

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