Ranitidine, also known by the brand name Zantac, is a histamine H 2 -receptor antagonist, also known as an H 2 -blocker, and an Antiulcer Agent. Ranitidine is used to treat certain ulcers and prevent their return. They are also used to treat some conditions, like Zollinger-Ellison disease, in which the stomach produces too much acid. They work by decreasing the amount of acid produced by the stomach.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Ranitidine may affect your baby. Also tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Tell your doctor as soon as possible if any of the following side effects occur: abdominal pain; back, leg, or stomach pain; bleeding or crusting sores on lips; blistering, burning, redness, scaling, or tenderness of skin ; blisters on palms of hands and soles of feet; changes in vision or blurred vision; confusion; coughing or difficulty in swallowing; dark-colored urine; dizziness; fainting; fast, pounding, or irregular heartbeat; fever and/or chills; flu-like symptoms; general feeling of discomfort or illness; hives; inflammation of blood vessels; joint pain; light-colored stools; mood or mental changes, including anxiety, agitation, confusion, hallucinations, mental depression, nervousness, or severe mental illness; muscle cramps or aches; nausea, vomiting, or loss of appetite; pain; peeling or sloughing of skin; red or irritated eyes; shortness of breath; skin rash or itching; slow heartbeat; sore throat; sores, ulcers, or white spots on lips, in mouth, or on genitals; sudden difficult breathing; swelling of face, lips, mouth, tongue, or eyelids; swelling of hands or feet; swollen or painful glands; tightness in chest; troubled breathing; unusual bleeding or bruising; unusual tiredness or weakness; unusually slow or irregular breathing; wheezing; and yellow eyes or skin.
The active ingredient in ZANTAC 150 Tablets, ZANTAC 300 Tablets, ZANTAC 25 EFFERdose Tablets, ZANTAC 150 EFFERdose Tablets, and ZANTAC Syrup is ranitidine hydrochloride (HCl), USP, a histamine H2-receptor antagonist. Chemically it is N[2-[[[5-[(dimethylamino)methyl] -2-furanyl]methyl]thio]ethyl] -N¢-methyl-2-nitro-1,1-ethenediamine, HCl. The empirical formula is C13H22N4O3S•HCl, representing a molecular weight of 350.87. Ranitidine HCl is a white to pale yellow, granular substance that is soluble in water. It has a slightly bitter taste and sulfurlike odor.
Each ZANTAC 150 Tablet for oral administration contains 168 mg of ranitidine HCl equivalent to 150 mg of ranitidine. Each tablet also contains the inactive ingredients FD&C Yellow No. 6 Aluminum Lake, hypromellose, magnesium stearate, microcrystalline cellulose, titanium dioxide, triacetin, and yellow iron oxide.
Each ZANTAC 300 Tablet for oral administration contains 336 mg of ranitidine HCl equivalent to 300 mg of ranitidine. Each tablet also contains the inactive ingredients croscarmellose sodium, D&C Yellow No. 10 Aluminum Lake, hypromellose, magnesium stearate, microcrystalline cellulose, titanium dioxide, and triacetin.
ZANTAC 25 EFFERdose Tablets for oral administration is an effervescent formulation of ranitidine that must be dissolved in water before use. Each individual tablet contains 28 mg of ranitidine HCl equivalent to 25 mg of ranitidine and the following inactive ingredients: aspartame, monosodium citrate anhydrous, povidone, and sodium bicarbonate. Each tablet also contains sodium benzoate. The total sodium content of each tablet is 30.52 mg (1.33 mEq) per 25 mg of ranitidine.
ZANTAC 150 EFFERdose Tablets for oral administration is an effervescent formulation of ranitidine that must be dissolved in water before use. Each individual tablet contains 168 mg of ranitidine HCl equivalent to 150 mg of ranitidine and the following inactive ingredients: aspartame, monosodium citrate anhydrous, povidone, and sodium bicarbonate. Each tablet also contains sodium benzoate. The total sodium content of each tablet is 183.12 mg (7.96 mEq) per 150 mg of ranitidine.
Each 1 mL of ZANTAC Syrup contains 16.8 mg of ranitidine HCl equivalent to 15 mg of ranitidine. ZANTAC Syrup also contains the inactive ingredients alcohol (7.5%), butylparaben, dibasic sodium phosphate, hypromellose, peppermint flavor, monobasic potassium phosphate, propylparaben, purified water, saccharin sodium, sodium chloride, and sorbitol.
Ranitidine has the following structural formula:
Brand name: Zantac :: Zantac 150 :: Zantac 300 :: Zantac 300 GELdose :: Zantac 75 :: Zantac EFFERdose :: Zantac GELdose
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