Protonix, or Pantoprazole, is used to treat certain conditions in which there is too much acid in the stomach. It is used to treat duodenal and gastric ulcers and gastroesophageal reflux disease (GERD), a condition in which the acid in the stomach washes back up into the esophagus.
Protonix works by decreasing the amount of acid produced by the stomach
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Protonix may affect your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Talk with your doctor as soon as possible if any of the following side effects occur: abdominal or stomach pain; blistering, loosening, peeling, or redness of skin; bull's eye-like rash on skin; changes in facial skin color; chest pain; diarrhea; difficulty in speaking; difficulty in urinating; discoloration, itching, numbness, pain, or redness at place of injection; fast or irregular breathing; increased frequency and volume of urination; infection; large, hive-like swellings on eyelids, face, lips, mouth, and/or tongue; loosening and/or stripping off of top layer of skin; loss of appetite; loss of vision; nausea; painful urination; pain in joints or muscles; puffiness or swelling of the eyelids or around the eyes; shortness of breath, troubled breathing, tightness in chest, and/or wheezing; skin rash, hives, and itching; skin tenderness with burning; unusual tiredness or weakness; unusual thirst; vomiting; or yellow eyes or skin.
The active ingredient in PROTONIX (pantoprazole sodium) Delayed- Release Tablets is a substituted benzimidazole, sodium 5-( difluoromethoxy)- 2- [[( 3,4- dimethoxy- 2- pyridinyl) methyl] sulfinyl]- 1 H- benzimidazole sesquihydrate, a compound that inhibits gastric acid secretion. Its empirical formula is C16 H14 F2 N3 NaO4 S x 1.5 H2 O, with a molecular weight of 432.4. Pantoprazole sodium sesquihydrate is a white to off- white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium sesquihydrate is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n- hexane. PROTONIX is supplied as a delayed- release tablet for oral administration, available in 2 strengths. Each delayed- release tablet contains 45.1 mg or 22.6 mg of pantoprazole sodium sesquihydrate (equivalent to 40 mg or 20 mg pantoprazole, respectively) with the following inactive ingredients: calcium stearate, crospovidone, hydroxypropyl methylcellulose, iron oxide, mannitol, methacrylic acid copolymer, polysorbate 80, povidone, propylene glycol, sodium carbonate, sodium lauryl sulfate, titanium dioxide, and triethyl citrate.
Protonix has the following structural formula: