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Prempro review by Pharmacy and Drugs ©
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Prempro, a combination of Conjugated Estrogens and Medroxyprogesterone, are estrogen and progestin hormones. Progestin lowers the effect of estrogen on the uterus and keeps problems from developing. Estrogens are given to: relieve the signs of menopause, such as hot flashes and unusual sweating, chills, faintness, or dizziness; to treat inflammation of the vagina and of the genital area by keeping these areas from becoming too dry, itchy, or painful; or to prevent the loss of bone that begins at the time of menopause.
Progestins are not needed if the uterus has been removed, and it may be better to receive estrogens alone.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
Avoid alcohol when taking this medicine.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Talk with your doctor as soon as possible if any of the following side effects occur: itching of the vagina or genital area; menstrual periods beginning again, including changing menstrual bleeding pattern for up to 6months; pain during sexual intercourse; or thick, white vaginal discharge.
PREMPRO 0.3 mg/1.5 mg therapy consists of a single tablet containing 0.3 mg of the conjugated estrogens (CE) found in Premarin tablets and 1.5 mg of medroxyprogesterone acetate (MPA) for oral administration.
PREMPRO 0.45 mg/1.5 mg therapy consists of a single tablet containing 0.45 mg of the conjugated estrogens found in Premarin tablets and 1.5 mg of medroxyprogesterone acetate for oral administration.
PREMPRO 0.625 mg/2.5 mg therapy consists of a single tablet containing 0.625 mg of the conjugated estrogens found in Premarin tablets and 2.5 mg of medroxyprogesterone acetate for oral administration.
PREMPRO 0.625 mg/5 mg therapy consists of a single tablet containing 0.625 mg of the conjugated estrogens found in Premarin tablets and 5 mg of medroxyprogesterone acetate for oral administration.
The conjugated estrogens found in Premarin tablets are a mixture of sodium estrone sulfate and sodium equilin sulfate, obtained exclusively from natural sources and blended to represent the average composition of materials derived from pregnant mares' urine. They contain as concomitant components, as sodium sulfate conjugates, 17 α-dihydroequilin, 17 α-estradiol and 17 ß-dihydroequilin.
Prempro has the following structural formula:
Generic name: Conjugated estrogen and medroxyprogesterone
Brand name(s): Premphase
Similar drugs: Etodolac ::
Vicodin ::
Ibuprofen
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