Plendil is one of a group of medicines used as antianginals, and antihypertensives. These medicines are also referred to as Calcium Channel Blocking Agents, and are used to increase the supply of blood and oxygen to the heart by relaxing blood vessels. They may be used to relieve and control angina or to control high blood pressure.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and NEVER stop taking Plendil without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Be very careful when exercising or indulging in any physical exertion. Chest pain resulting from exercise or physical exertion is reduced or prevented by this medicine, and you may be unaware when you are overdoing it.
You may get a headache after taking a dose of this medicine. This usually fades the longer you take the medication, but you should contact your doctor if the headaches are severe, or you continue to have them. You may also notice tenderness, swelling, or bleeding of the gums when you start this medication. Regular brushing and flossing and massaging your gums may help with this problem.
Check with your doctor as soon as possible if any of the following side effects occur: difficulty breathing, coughing, or wheezing; irregular heartbeat; skin rash; or swelling of ankles, feet, or lower legs. Also watch for: bleeding, tender, or swollen gums; chest pain (within about 30 minutes of taking the medicine); fainting; painful, swollen joints; or if you’re having trouble seeing. Tell your doctor if you have any of these symptoms.
You may also experience constipation; diarrhea; dizziness or lightheadedness; flushing of the skin; headache; nausea, and unusual tiredness or weakness. These symptoms usually fade the longer you take Plendil.
PLENDIL (felodipine) is a calcium antagonist (calcium channel blocker). Felodipine is a dihydropyridine derivative that is chemically described as ± ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5- pyridinedicarboxylate. Its empirical formula is C18H19Cl2NO4. Felodipine is a slightly yellowish, crystalline powder with a molecular weight of 384.26. It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture. Tablets PLENDIL provide extended release of felodipine. They are available as tablets containing 2.5 mg, 5 mg, or 10 mg of felodipine for oral administration. In addition to the active ingredient felodipine, the tablets contain the following inactive ingredients: Tablets PLENDIL 2.5 mg — hydroxypropyl cellulose, lactose, FD&C Blue 2, sodium stearyl fumarate, titanium dioxide, yellow iron oxide, and other ingredients. Tablets PLENDIL 5 mg and 10 mg — cellulose, red and yellow oxide, lactose, polyethylene glycol, sodium stearyl fumarate, titanium dioxide, and other ingredients.
Plendil has the following structural formula: