Plavix, also known as Clopidogrel, is used to lessen the chance of heart attack or stroke. It is for people who have already had a heart attack or stroke or with other blood circulation problems that could lead to a stroke or heart attack. Plavix reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together that may also increase the chance of serious bleeding in some patients.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and never stop taking Plavix without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Talk with your doctor immediately if any of the following side effects occur: red or purple spots on skin, varying in size from pinpoint to large bruises; nosebleed; vomiting of blood or material that looks like coffee grounds; black, tarry stools; blistering, flaking, or peeling of skin; blood in urine or stools; fever, chills, or sore throat; headache; stomach pain; ulcers, sores, or white spots in mouth; unusual bleeding or bruising; or weakness.
PLAVIX (clopidogrel bisulfate) is an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Chemically it is methyl (+)-(S)-a-(2-chlorophenyl) -6,7-dihydrothieno [3,2-c]pyridine-5(4H)-acetate sulfate (1:1). The empirical formula of clopidogrel bisulfate is C16 H16ClNO2S•H2SO4 and its molecular weight is 419.9. Plavix for oral administration is provided as pink, round, biconvex, debossed film-coated tablets containing 97.875 mg of clopidogrel bisulfate which is the molar equivalent of 75 mg of clopidogrel base. Each tablet contains hydrogenated castor oil, hydroxypropylcellulose, mannitol, microcrystalline cellulose and polyethylene glycol 6000 as inactive ingredients. The pink film coating contains ferric oxide, hypromellose 2910, lactose monohydrate, titanium dioxide and triacetin. The tablets are polished with Carnauba wax.
Plavix has the following structural formula: