|
Percocet-5/325
This page contains drug information on Percocet-5/325.
The information provided includes the following:
- what is Percocet-5/325
- the possible side effects of Percocet-5/325
- what happens if you miss a dose of Percocet-5/325
- what happens if you overdose with Percocet-5/325
- the most important information about Percocet-5/325
- how to use Percocet-5/325
- other drugs that may affect Percocet-5/325
- what to avoid while using Percocet-5/325
|
|
Generic Name: acetaminophen and oxycodone (a see tah MIH no
fen and ox ee KOE done)
Brand Names:
Endocet, Percocet-10/ 650, Percocet-2.5/ 325, Percocet-5/ 325,
Percocet-7.5/ 500, Roxicet, Roxilox, Tylox |
|
What is the most important information I should know about
acetaminophen and oxycodone?
|
|
• |
Do not stop taking acetaminophen and oxycodone suddenly if you have
been taking it continuously for more than 5 to 7 days. Stopping suddenly
could cause withdrawal symptoms and make you feel uncomfortable. Your
doctor may want to gradually reduce your dose. |
|
• |
Use caution when driving, operating machinery, or performing other
hazardous activities. Oxycodone may cause drowsiness or dizziness. If
you experience drowsiness or dizziness, avoid these activities. |
|
• |
Avoid alcohol while taking acetaminophen and oxycodone. Alcohol may
increase the drowsiness and dizziness caused by acetaminophen and
oxycodone and could be dangerous. Also, acetaminophen can be toxic to
your liver when taken with as little as 2 drinks of alcohol. |
|
• |
Also avoid sleeping pills, tranquilizers, sedatives, and
antihistamines except under the supervision of your doctor. These
medications also may cause dangerous sedation. |
|
• |
Acetaminophen and oxycodone may cause constipation. Drink plenty of
water (six to eight full glasses a day) to lessen this side effect.
Increasing the amount of fiber in your diet can also help to alleviate
constipation. |
|
• |
Never take more acetaminophen and oxycodone than is prescribed for
you. If your
pain is not being adequately treated, talk to your doctor. |
|
• |
Watch the acetaminophen content of other over-the-counter and
prescription products while taking this medication. Do not take more
than a total of 4 grams (4000 mg) of acetaminophen per day. |
|
What is acetaminophen and oxycodone?
|
|
• |
Oxycodone (related to codeine) is in a class of drugs called
narcotic analgesics. It relieves pain. |
|
• |
Acetaminophen is a less potent
pain reliever that increases the effects of oxycodone. |
|
• |
Together, acetaminophen and oxycodone are used to relieve
moderate-to-severe pain. |
|
• |
Acetaminophen and oxycodone may also be used for purposes other than
those listed in this medication guide. |
|
Who should not take acetaminophen and oxycodone?
|
|
• |
Before taking acetaminophen and oxycodone, tell your doctor if you
have |
| |
· |
a history of alcohol or drug addiction. |
|
• |
You may not be able to take acetaminophen and oxycodone, or you may
require a dosage adjustment or special monitoring during treatment if
you have any of the conditions listed above. |
|
• |
This drug combination is in the FDA pregnancy category C. This means
that it is not known whether it will harm an unborn baby. Do not take
this medication without first talking to your doctor if you are pregnant. |
|
• |
It is not known whether this drug combination passes into breast
milk. Do not take acetaminophen and oxycodone without first talking to
your doctor if you are breast-feeding a baby. |
|
• |
If you are younger than 18 years of age or older than 60 years of
age, you may be more likely to experience side effects from
acetaminophen and oxycodone therapy. Use extra caution. |
|
How should I take acetaminophen and oxycodone?
|
|
• |
Take acetaminophen and oxycodone exactly as directed by your doctor.
If you do not understand these directions, ask your pharmacist, nurse,
or doctor to explain them to you. |
|
• |
Take each dose with a full glass of water. |
|
• |
Take acetaminophen and oxycodone with food or milk if it upsets your
stomach. |
|
• |
Never take more acetaminophen and oxycodone than is prescribed for
you. Too much acetaminophen and oxycodone could be very harmful. |
|
• |
To ensure that you get a correct dose, measure the liquid form of
oxycodone with a special dose-measuring spoon or cup, not with a regular
table spoon. If you do not have a dose-measuring device, ask your
pharmacist where you can get one. |
|
• |
Do not stop taking acetaminophen and oxycodone suddenly if you have
been taking it continuously for more than 5 to 7 days. Stopping suddenly
could cause withdrawal symptoms and make you feel uncomfortable. Your
doctor may want to gradually reduce your dose. |
|
• |
Acetaminophen and oxycodone may cause constipation. Drink plenty of
water (six to eight full glasses a day) to lessen this side effect.
Increasing the amount of fiber in your diet can also help to alleviate
constipation. |
|
• |
Do not share this medication with anyone else. |
|
• |
Store acetaminophen and oxycodone at room temperature away from
moisture and heat. |
|
What happens if I miss a dose?
|
|
• |
Take the missed dose as soon as you remember. Do not take a
double dose of this medication. Wait the prescribed amount of time
before taking your next dose. |
|
What happens if I overdose?
|
|
• |
Seek emergency medical attention. |
|
• |
Symptoms of an acetaminophen and oxycodone overdose include slow
breathing, seizures, dizziness, weakness, loss of consciousness, coma,
confusion, tiredness, cold and clammy skin, small pupils, nausea,
vomiting, and sweating. |
|
What should I avoid while taking acetaminophen and oxycodone?
|
|
• |
Use caution when driving, operating machinery, or performing other
hazardous activities. Oxycodone may cause drowsiness or dizziness. If
you experience drowsiness or dizziness, avoid these activities. |
|
• |
Avoid alcohol while taking acetaminophen and oxycodone. Alcohol may
increase the drowsiness and dizziness caused by acetaminophen and
oxycodone and could be dangerous. Also, acetaminophen can be toxic to
your liver when taken with as little as 2 drinks of alcohol. |
|
• |
Also avoid sleeping pills, tranquilizers, sedatives, and
antihistamines except under the supervision of your doctor. These
medications also may cause dangerous sedation. |
|
• |
Watch the acetaminophen content of other over-the-counter and
prescription products while taking this medication. Do not take more
than a total of 4 grams (4000 mg) of acetaminophen per day. |
|
What are the possible side effects of acetaminophen and oxycodone?
|
|
• |
If you experience any of the following serious side effects, stop
taking acetaminophen and oxycodone and seek emergency medical attention
or notify your doctor immediately: |
| |
· |
an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives); |
| |
· |
severe weakness or dizziness; |
| |
· |
yellowing of the skin or eyes; or |
| |
· |
unusual fatigue, bleeding, or bruising. |
|
• |
Other, less serious side effects may be more likely to occur.
Continue to take acetaminophen and oxycodone and talk to your doctor if
you experience |
| |
· |
dry mouth, nausea, vomiting, or decreased appetite; |
| |
· |
dizziness, tiredness, or lightheadedness; |
| |
· |
decreased urination; or |
|
• |
Acetaminophen and oxycodone is habit forming. Do not stop taking it
suddenly. |
|
• |
Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
|
What other drugs will affect acetaminophen and oxycodone?
|
|
• |
Do not take acetaminophen and oxycodone if you have taken a
monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan),
phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.
Dangerous side effects could result. |
|
• |
The most serious interactions affecting acetaminophen and oxycodone
are with those drugs that also cause sedation. The following drugs may
lead to dangerous sedation if taken with acetaminophen and oxycodone: |
| |
· |
antihistamines such as brompheniramine (Dimetane, Bromfed, others),
diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton,
Teldrin, others), and others; |
| |
· |
tricyclic
antidepressants, such as amitriptyline (Elavil) and doxepin (Sinequan),
and serotonin reuptake inhibitors such as fluoxetine (Prozac),
sertraline (Zoloft), and paroxetine (Paxil); |
| |
· |
other commonly used antidepressants, including amoxapine (Asendin),
clomipramine (Anafranil), desipramine (Norpramin), imipramine
(Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil); |
| |
· |
anticholinergics such as belladonna (Donnatal), clidinium (Quarzan),
dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz),
ipratropium (Atrovent), propantheline (Pro-Banthine), and scopolamine
(Transderm-Scop); |
| |
· |
phenothiazines such as chlorpromazine (Thorazine), fluphenazine
(Prolixin), thioridazine (Mellaril), and prochlorperazine (Compazine);
and |
| |
· |
tranquilizers and sedatives such as phenobarbital (Solfoton,
Luminal), amobarbital (Amytal), secobarbital (Seconal), alprazolam
(Xanax), diazepam (Valium), lorazepam (Ativan), flurazepam (Dalmane),
and temazepam (Restoril). |
|
• |
You may not be able to take acetaminophen and oxycodone or you may
require a dosage adjustment or special monitoring during treatment if
you are taking any of the medicines listed above. |
|
• |
Watch the acetaminophen content of other over-the-counter and
prescription products while taking this medication. Do not take more
than a total of 4 grams (4000 mg) of acetaminophen per day. |
|
• |
Drugs other than those listed here may also interact with
acetaminophen and oxycodone. Talk to your doctor and pharmacist before
taking any prescription or over-the-counter medicines. |
|
Where can I get more information?
|
|
• |
Your pharmacist has additional information about acetaminophen and
oxycodone written for health professionals that you may read. |
|
• |
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
|
• |
Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic
reactions, or adverse effects. If you have questions about the drugs you
are taking, check with your doctor, nurse or pharmacist. |
Copyright 1996-2006 Cerner Multum, Inc. Version: 7.01. Revision date: 2/
17/ 06. |
|