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    Nexium
Nexium capsules Nexium review
by
Pharmacy and Drugs


     .: Prescription

Nexium, called Esomeprazole, is used to treat duodenal ulcers and gastroesophageal reflux disease (GERD), which is a condition in which the acid in the stomach washes back up into the esophagus. It also reduces the chance of gastric ulcers in patients who use NSAIDs and who may be at greater risk of ulcers. Sometimes Nexium is used with antibiotics to treat ulcers associated with infection caused by the H. pylori bacteria. Nexium works by decreasing the amount of acid produced by the stomach.

Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.

It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Nexium just because you start to feel better. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.

Tell your doctor immediately if any of the following side effects occur: blistering, peeling, loosening of skin; bloating; chills; cough; darkened urine; difficulty swallowing; dizziness; fast heartbeat; fever; hives; indigestion; itching; joint or muscle pain; loss of appetite; pains in stomach, side, or abdomen, possibly radiating to the back; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; red irritated eyes; red skin lesions, often with a purple center; shortness of breath; skin rash; sore throat; sores, ulcers, or white spots in mouth or on lips; tightness in chest; unusual tiredness or weakness; vomiting; wheezing; or yellow eyes or skin.

The active ingredient in NEXIUM (esomeprazole magnesium) Delayed-Release Capsules is bis(5-methoxy-2-[(S)-[ (4-methoxy-3,5-dimethyl-2-pyridinyl) methyl]sulfinyl]-1H-benzimidazole-1-yl) magnesium trihydrate, a compound that inhibits gastric acid secretion. Esomeprazole is the S-isomer of omeprazole, which is a mixture of the S- and R- isomers. Its empirical formula is (C17H18N3O3S)2Mg x 3 H2O with molecular weight of 767.2 as a trihydrate and 713.1 on an anhydrous basis. The magnesium salt is a white to slightly colored crystalline powder. It contains 3 moles of water of solvation and is slightly soluble in water. NEXIUM is supplied as Delayed-Release Capsules for oral administration. Each delayed-release capsule contains 20 mg or 40 mg of esomeprazole (present as 22.3 mg or 44.5 mg esomeprazole magnesium trihydrate) in the form of enteric-coated pellets with the following inactive ingredients: glyceryl monostearate 40-50, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer type C, polysorbate 80, sugar spheres, talc, and triethyl citrate. The capsule shells have the following inactive ingredients: gelatin, FD&C Blue #1, FD&C Red #40, D&C Red #28, titanium dioxide, shellac, ethyl alcohol, isopropyl alcohol, n-butyl alcohol, propylene glycol, sodium hydroxide, polyvinyl pyrrolidone, and D&C Yellow #10.

Nexium has the following structural formula:

Nexium chemical structure
Generic name: Esomeprazole

Brand name(s):

Similar drugs: Metronidazole :: Prilosec :: Rabeprazole

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