Nasonex, also called Mometasone, belongs to the family of medicines known as corticosteroids, which belong to the family of medicines called steroids. Nasonex is sprayed into the nose to help relieve stuffy nose, irritation, and the discomfort of hay fever and other allergies, and is also used to treat nasal polyps in adults.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more medicine than directed. If you miss a dose of this medicine, take it as soon as you remember, unless it is the next day. In that case, skip it and continue with your regularly scheduled dose. Do NOT double doses.
Tell your doctor as soon as possible if any of the following side effects occur: bloody mucus or unexplained nosebleeds; cold or flu-like symptoms; increased abdominal pain and cramping during menstrual periods; muscle or bone pain; stuffy or runny nose or headache; viral infections; chest pain; cough; discharge or redness in the eye, eyelid, or inner lining of the eyelid; earache; shortness of breath, troubled breathing, tightness in chest, or wheezing; sores inside nose; or white patches inside nose or mouth.
Mometasone furoate monohydrate, the active component of NASONEX Nasal Spray, 50 µg, is an anti- inflammatory corticosteroid having the chemical name, 9,21-Dichloro-11ß, 17-dihydroxy-16a -methylpregna-1, 4-diene-3,20-dione 17-(2-furoate) monohydrate. Mometasone furoate monohydrate is a white powder, with an empirical formula of C27H30Cl2O6 • H2O and a molecular weight of 539.45. It is practically insoluble in water; slightly soluble in methanol, ethanol, and isopropanol; soluble in acetone and chloroform; and freely soluble in tetrahydrofuran. Its partition coefficient between octanol and water is greater than 5000. NASONEX Nasal Spray, 50 µg is a metered-dose, manual pump spray unit containing an aqueous suspension of mometa- sone furoate monohydrate equivalent to 0.05% w/w mometasone furoate calculated on the anhydrous basis; in an aqueous medium containing glycerin, microcrystalline cellulose and carboxymethylcellulose sodium, sodium citrate, 0.25% w/w phenylethyl alcohol, citric acid, benzalkonium chloride, and polysorbate 80. The pH is between 4.3 and 4.9.
Nasonex has the following structural formula: