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Naprosyn Naprosyn review
Pharmacy and Drugs

     .: Prescription

In 1976, Naprosyn was introduced as a non-steroidal anti-inflammatory drug, commonly referred to as NSAIDs. It hit the market as a prescription only drug, and in most cases it still is. Low dose Naprosyn is available in Australia, and low dose forms of Naprosyn are available in the United States as over the counter medications.

Low dose over the counter forms of Naprosyn include Aleve and Aleve products. Similar products are prevalent in over the counter cough and cold medicine as well as allergy relievers.

Naprosyn, also prescribed as Anaprox and Naprelan, is commonly used to treat bone and joint pain as well as menstrual pain and the effects of chronic diseases such as gout, osteoarthritis, rheumatoid arthritis, bursitis, tendonitis, ankylosing spondylitis, and acute injury pain.

Naprosyn is known to cause upset stomachs if it is not taken with food, however sever nausea should not occur. Dizziness, headaches, diarrhea or constipation, depression, fatigue or weakness, skipped menstrual period and a dry mouth are all fairly common, low impact side effects related to all NSAIDs. Avoiding sunlight exposure is recommended for patients, especially those with rheumatoid diseases, as Naprosyn causes sensitivity to sun exposure.

Those patients who suffer from allergic reactions to aspirin or other types of pain relievers should not take Naprosyn. An allergic reaction is quite obvious as it presents with hives, swelling of the face, throat, tongue, or lips. An allergic reaction requires urgent medical intervention.

The National Institute of Health began and ceased a five year study on the likelihood that Naprosyn had a positive effect on preventing Alzheimer’s. The study was terminated because of a dramatic 50% increase in possibility of a stroke or heart attack.

There is conflicting evidence as to whether Naprosyn has any effect on an unborn fetus. While it is known that Naprosyn can cause heart complications in the baby if taken late in the third trimester, studies are now considering that the heart may possibly be affected if Naprosyn is taken at any time during pregnancy. Physicians should use caution when prescribing Naprosyn to pregnant women. The medication is passed through the breast milk and great care should be taken if there is consideration for prescribing this medication to a nursing mother.

Naprosyn has a lengthy list of possible interactions with other medications, including over the counter cough and cold medicines and other pain relievers. Blood thinners, steroids, insulin and oral diabetic medications, lithium, probenecid, and the active ingredient in Pepto Bismol are some of the more common side effects. Drinking more than three alcoholic beverages a day can lead to stomach bleeding. Stomach bleeding, or bloody, terry, or black stools can occur without warning and should be reported to the prescribing physician as they are typically indicative of stomach or bowel damage.

An overdose on Naprosyn requires immediate medical attention. A patient who has overdosed may present with severe nausea, vomiting and stomach pain, dizziness and drowsiness, headache and diminished hearing, blurry vision, profuse sweating, seizures or numbness and tingling sensations, slow breathing, or an inability to excrete urine.

Naprosyn or any related NSAID should be prescribed to a patient with kidney, liver, or heart disease. Heavy drinkers, patients with ulcers, high blood pressure, or fluid retention should not be administered the drug. Those with aspirin allergies, coagulant disorders, or congestive heart failure may have fatal reactions to the drug.

For nearly thirty five years Naprosyn has been an effective pain reliever and a quality alternative to narcotic medications for relieving pain. Patients who are successfully prescribed the drug report a significant decrease in their daily pain.

Naproxen has a molecular weight of 230.26 and a molecular formula of C14H14O3. Naproxen sodium has a molecular weight of 252.23 and a molecular formula of C14H13NaO3. Naproxen is an odorless, white to off-white crystalline substance. It is lipid-soluble, practically insoluble in water at low pH and freely soluble in water at high pH. The octanol/water partition coefficient of naproxen at pH 7.4 is 1.6 to 1.8. Naproxen sodium is a white to creamy white, crystalline solid, freely soluble in water at neutral pH.
NAPROSYN (naproxen tablets) is available as yellow tablets containing 250 mg of naproxen, pink tablets containing 375 mg of naproxen and yellow tablets containing 500 mg of naproxen for oral administration. The inactive ingredients are croscarmellose sodium, iron oxides, povidone and magnesium stearate.
NAPROSYN (naproxen suspension) is available as a light orange-colored opaque oral suspension containing 125 mg/5 mL of naproxen in a vehicle containing sucrose, magnesium aluminum silicate, sorbitol solution and sodium chloride (30 mg/5 mL, 1.5 mEq), methylparaben, fumaric acid, FD&C Yellow No. 6, imitation pineapple flavor, imitation orange flavor and purified water. The pH of the suspension ranges from 2.2 to 3.7.

Naprosyn has the following structural formula:

Chemical structure of Naprosyn
Generic name: Naproxen

Brand name(s): Aleve :: Aleve Caplet :: Anaprox :: Anaprox-DS :: EC Naprosyn :: Naprelan

Similar drugs: Nabumetone :: Hydrocodone :: Mobic

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