Monopril is one of a class of drugs known as ACE Inhibitors. When used as an antihypertensive, Monopril helps lower high blood pressure. As a vasodilator, Monopril may be used to treat congestive heart failure.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as use during pregnancy can cause low blood pressure, severe kidney failure, too much potassium, or even the death of your baby.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor if you have any signs of infection (chills, fever, or sore throat), or have severe or continuing diarrhea, or notice any signs of jaundice (yellowing of skin or eyes). Be especially careful during exercise or hot weather. Get immediate medical attention if you experience any welts or swelling around your face, throat or tongue.
MONOPRIL (fosinopril sodium tablets) is the sodium salt of fosinopril, the ester prodrug of an angiotensin converting enzyme (ACE) inhibitor, fosinoprilat. It contains a phosphinate group capable of specific binding to the active site of angiotensin converting enzyme. Fosinopril Sodium is Designated Chemically as : L-proline, 4-cyclohexyl-1-[[[2-methyl-1- (1-oxopropoxy) propoxyl] (4-phenylbutyl) phosphinyl]acetyl]-, sodium salt, trans-. Fosinopril sodium is a white to off-white crystalline powder. It is soluble in water (100 mg/ml), methanol, and ethanol and slightly soluble in hexane. Its empiric formula is C30H45NNaO7P, and its molecular weight is 585.65. Monopril is available for oral administration as 10 mg, 20 mg and 40 mg tablets. Inactive ingredients include: lactose, microcrystalline cellulose, crospovidone, povidone, and sodium stearyl fumarate.
Monopril has the following structural formula: