Lotensin is one of a class of drugs known as ACE Inhibitors. When used as an antihypertensive, Lotensin helps lower high blood pressure. As a vasodilator, Lotensin may be used to treat congestive heart failure.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as use during pregnancy can cause low blood pressure, severe kidney failure, too much potassium, or even the death of your baby.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor if you have any signs of infection (chills, fever, or sore throat), or have severe or continuing diarrhea, or notice any signs of jaundice (yellowing of skin or eyes). Be especially careful during exercise or hot weather. Get immediate medical attention if you experience any welts or swelling around your face, throat or tongue.
Benazepril hydrochloride is a white to off-white crystalline powder, soluble (>100 mg/mL) in water, in ethanol, and in methanol. Its chemical name is 3-[[1-(ethoxy-carbonyl)-3- phenyl-(1S)-propyl]amino]- 2,3,4,5-tetrahydro-2- oxo-1H-1-(3S)- benzazepine-1-acetic acid monohydrochloride. Its empirical formula is C24H28N2O5•HCl, and its molecular weight is 460.96. Lotensin is supplied as tablets containing 5 mg, 10 mg, 20 mg, and 40 mg of benazepril hydrochloride for oral administration. The inactive ingredients are colloidal silicon dioxide, crospovidone, hydrogenated castor oil (5-mg, 10-mg, and 20-mg tablets), hypromellose, iron oxides, lactose, magnesium stearate (40-mg tablets), microcrystalline cellulose, polysorbate 80, propylene glycol (5-mg and 40-mg tablets), starch, talc, and titanium dioxide.
Lotensin has the following structural formula: