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Lopid Lopid review
Pharmacy and Drugs

     .: Prescription

Gemfibrozil is a drug for dyslipidemia. The exact mechanism that gemfibrozil works to reduce cholesterol (hypercholesterolemia) and triglycerides (types of fat) in the blood is not known. High levels of fat in the blood are associated with an increased chance of heart disease, strokes, and other illnesses. It is important to follow a special diet and exercise plan recommended by your doctor while taking this medication. Lifestyle modification is also crucial in regulating cholesterol level in the bloodstream.

Before taking this medication, tell your doctor if you have any liver disease; kidney disease; or gallbladder disease. You may not be able to take gemfibrozil, or you may require a dosage adjustment or special monitoring during treatment if you have any of the aforementioned conditions.

Gemfibrozil is not known to be harmful to an unborn baby and whether it passes into breast milk. Do not take this medication without first talking to your doctor if you are pregnant or plan to get pregnant and if you are breast-feeding during treatment.

It is important to take gemfibrozil regularly as directed by your doctor to get the most benefit. It may take up to 3 months before you can see any desirable change of blood cholesterol level so do not stop taking this drug unless instructed by your doctor. To properly monitor progress to treatment and detect any side effects, blood chemistry tests may be requested during treatment with gemfibrozil.

Gemfibrozil overdose symptoms may include diarrhea, headache, and myalgia (muscle pain). An overdose of this medication is unlikely to threaten life nevertheless, call emergency room or poison control for advice if you take too much of this drug.

Use caution with driving, operating machinery, and performing other hazardous activities until you know how gemfibrozil affects you. It may cause some drowsiness or dizziness, especially at the start of therapy.

Serious side effects of this medicine may include the following: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); chest pain, shortness of breath, or an irregular heartbeat; nausea, vomiting, stomach pain, or clay-colored stools; yellowish discoloration of the skin or eyes (jaundice); rash or itching; lip or mouth sores; swollen legs or feet; chills, fever, or blood in the urine; or muscle aches, pain, or cramping.

Other, less serious side effects may be more likely to occur these may include indigestion; headache, dizziness, or drowsiness; or decreased sex drive. Always inform your doctor about any other unusual side effect that you may experience.

Gemfibrozil may increase the effects of the following drugs, which could lead to dangerous side effects: an anticoagulant (blood thinner) such as warfarin (Coumadin); insulin or an oral diabetes medication such as chlorpropamide (Diabenese), glipizide (Glucotrol), glyburide (Micronase, DiaBeta, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), and acetohexamide (Dymelor), and others; or another cholesterol-lowering drug such as atorvastatin (Lipitor), lovastatin (Mevacor, Altocor), simvastatin (Zocor), pravastatin (Pravachol), fluvastatin (Lescol, Lescol XL) .

Drugs other than those listed here may also interact with gemfibrozil. It is best to talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

The empirical formula is C15H22O3 and the molecular weight is 250.35; the solubility in water and acid is 0.0019% and in dilute base it is greater than 1%. The melting point is 58-61C. Gemfibrozil is a white solid which is stable under ordinary conditions. Each tablet contains 600 mg gemfibrozil. Each also contains calcium stearate; candelilla wax FCC; microcrystalline cellulose; hydroxypropyl cellulose; hydroxypropyl methylcellulose, USP; methylparaben, NF; Opaspray white; polyethylene glycol; polysorbate 80; propylparaben; colloidal silicon dioxide; pregelatinized starch.

Lopid has the following structural formula:

Lopid chemical structure
Generic name: Gemfibrozil

Brand name(s):

Similar drugs: Lipitor :: Rosuvastatin :: Zocor

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