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    Lipitor
Lipitor tablets Lipitor review
by
Pharmacy and Drugs


     .: Prescription

Lipitor, also known as Atorvastatin, is used to lower levels of cholesterol and other fats in the blood. Lipitor belongs to the group of medicines called 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors. They work by blocking an enzyme that is needed to make cholesterol.

Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as Lipitor may have unwanted effects on your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.

It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Lipitor without discussing it with your doctor first.

If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.

Talk with your doctor as soon as possible if any of the following side effects occur: fever; muscle aches or cramps; severe stomach pain; or unusual tiredness or weakness.

IPITOR (atorvastatin calcium) is a synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin calcium is [R-(R*, R*)]-2-(4-fluorophenyl)-b, d -dihydroxy-5- (1-methylethyl)-3-phenyl- 4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate. The empirical formula of atorvastatin calcium is (C33H34 FN2O5)2Ca·3H2O and its molecular weight is 1209.42. Atorvastatin calcium is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below. Atorvastatin calcium is very slightly soluble in distilled water, pH 7.4 phosphate buffer, and acetonitrile, slightly soluble in ethanol, and freely soluble in methanol. LIPITOR tablets for oral administration contain 10, 20, 40 or 80 mg atorvastatin and the following inactive ingredients: calcium carbonate, USP; candelilla wax, FCC; croscarmellose sodium, NF; hydroxypropyl cellulose, NF; lactose monohydrate, NF; magnesium stearate, NF; microcrystalline cellulose, NF; Opadry White YS-1-7040 (hypromellose, polyethylene glycol, talc, titanium dioxide); polysorbate 80, NF; simethicone emulsion.

Lipitor has the following structural formula:

Lipitor chemical 
structure
Generic name: Atorvastatin

Brand name(s):

Similar drugs: Ramipril :: Perindopril :: Diovan HCT

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