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What is the most important information I should know about
levofloxacin?
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Take all of the levofloxacin that has been prescribed for you even
if you begin to feel better. Your symptoms may start to improve before
the infection is completely treated. |
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Take each dose with a full glass of water (8 ounces). Drink several
extra glasses of fluid each day to prevent the formation of levofloxacin
crystals in the urine. |
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Do not take antacids that contain magnesium or aluminum (e.g., Tums
or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or
mineral supplements that contain iron or zinc for a minimum of 2 hours
before or 2 hours after a dose of levofloxacin. Taking antacids,
sucralfate, or vitamin or mineral supplements too close to a dose of
levofloxacin can greatly decrease the effects of the antibiotic. |
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Levofloxacin is an antibiotic in a class of drugs called
fluoroquinolones. It fights bacteria in the body. |
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Levofloxacin is used to treat various types of bacterial infections. |
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Levofloxacin may also be used for purposes other than those listed
in this medication guide. |
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What should I discuss with my healthcare provider before taking
levofloxacin?
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Before taking levofloxacin, tell your doctor if you |
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have a seizure disorder; |
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have a heart condition known as prolongation of the QT interval; |
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have a slow heart rate that is considered a medical condition; |
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have low levels of potassium in your
blood; or |
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are being treated for heart rhythm disturbances (irregular
heartbeats) with drugs such as quinidine (Cardioquin, Quinidex,
Quinaglute, others), procainamide (Pronestyl, Procan SR, others),
amiodarone (Cordarone, Pacerone, others), sotalol (Betapace), and others. |
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You may not be able to take levofloxacin, or you may require a
dosage adjustment or special monitoring during treatment if you have any
of the conditions listed above. |
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Levofloxacin is in the FDA pregnancy category C. This means that it
is not known whether levofloxacin will be harmful to an unborn baby. Do
not take this medication without first talking to your doctor if you are
pregnant or could become pregnant during treatment. |
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It is not known whether levofloxacin passes into breast milk.
Similar drugs are known to affect bone development. Do not take
levofloxacin without first talking to your doctor if you are
breast-feeding a baby. |
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Levofloxacin is not approved for use by children under 18 years of
age. It may interfere with bone development. |
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How should I take levofloxacin?
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Take levofloxacin exactly as directed by your doctor. If you do not
understand these instructions, ask your pharmacist, nurse, or doctor to
explain them to you. |
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Take each dose with a full glass of water (8 ounces). Drink several
extra glasses of fluid each day to prevent the formation of levofloxacin
crystals in the urine. |
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Levofloxacin may be taken with or without food. |
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Take levofloxacin at evenly spaced intervals. |
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Do not take antacids that contain magnesium or aluminum (e.g., Tums
or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or
mineral supplements that contain iron or zinc for a minimum of 2 hours
before or 2 hours after a dose of levofloxacin. Taking antacids,
sucralfate, or vitamin or mineral supplements too close to a dose of
levofloxacin can greatly decrease the effects of the antibiotic. |
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• |
Take all of the levofloxacin that has been prescribed for you even
if you begin to feel better. Your symptoms may start to improve before
the infection is completely treated. |
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Store this medication at room temperature away from moisture and
heat. |
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What happens if I miss a dose?
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Take the missed dose as soon as you remember. However, if it is
almost time for the next dose, skip the missed dose and take only the
next regularly scheduled dose. Do not take a double dose of this
medication unless otherwise directed by your doctor. |
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What happens if I overdose?
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Seek emergency medical attention. |
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The most common symptom of a levofloxacin overdose is seizures. |
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What should I avoid while taking levofloxacin?
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Avoid prolonged exposure to sunlight. Levofloxacin may increase the
sensitivity of the skin to sunlight, and a severe sunburn may result. If
sun exposure is unavoidable, wear protective clothing and sunscreen.
Call your doctor if you experience severe burning, redness, itching,
rash, or swelling after exposure to the sun. |
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Use caution when driving, operating machinery, or performing other
hazardous activities. Levofloxacin may cause dizziness. If you
experience dizziness, avoid these activities. |
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What are the possible side effects of levofloxacin?
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If you experience any of the following serious side effects, stop
taking levofloxacin and seek emergency medical attention or contact your
doctor immediately: |
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an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives); |
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confusion or hallucinations; |
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irregular heartbeats, chest
pain, or fainting; |
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liver damage (yellowing of the skin or eyes, nausea, abdominal pain
or discomfort, unusual bleeding or bruising, severe fatigue); or |
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If you experience any of the following less serious side effects,
continue taking levofloxacin and talk to your doctor: |
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nausea, vomiting, diarrhea, or constipation; |
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headache or lightheadedness; |
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ringing in the ears; or |
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increased sensitivity of the skin to sunlight. |
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Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect levofloxacin?
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Do not take antacids that contain magnesium or aluminum (e.g., Tums
or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or
mineral supplements that contain iron or zinc for a minimum of 2 hours
before or 2 hours after a dose of levofloxacin. Taking antacids,
sucralfate, or vitamin or mineral supplements too close to a dose of
levofloxacin can greatly decrease the effects of the antibiotic. |
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Before taking levofloxacin, tell your doctor if you are taking any
of the following drugs: |
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theophylline (Theo-Dur, Theolair, Slo-Phyllin, Slo-Bid, Elixophyllin); |
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insulin or an oral diabetes medication such as glipizide (Glucotrol),
glyburide (Micronase, Diabeta, Glynase), and others; or |
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a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin,
Advil, Nuprin, others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen
(Orudis KT, Orudis, Oruvail), and others. |
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You may not be able to take levofloxacin, or you may require a
dosage adjustment or special monitoring during treatment if you are
taking any of the medicines listed above. |
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Drugs other than those listed here may also interact with
levofloxacin. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines, including herbal products. |
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Where can I get more information?
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Your pharmacist has additional information about levofloxacin
written for health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this medicine
only for the indication prescribed. |
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Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2004 Cerner Multum, Inc. Version: 4.05. Revision date: 11/
11/ 04. |