Levaquin, or Levofloxacin, belongs to the class of medicines known as antibiotics. It is used to treat bacterial infections in many different parts of the body. Levaquin is also used to treat anthrax. Levaquin works by killing bacteria or preventing their growth.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor immediately if any of the following side effects occur: skin rash, itching, or redness.
Tell your doctor as soon as possible if any of the following side effects occur: abdominal or stomach cramps or pain; abdominal tenderness; agitation; blisters; confusion; diarrhea which may also be bloody; fever; hallucinations; pain, inflammation, or swelling in calves of legs, shoulders, or hands; psychosis; sensation of skin burning; redness and swelling of skin; or trembling.
LEVAQUIN (levofloxacin) is a synthetic broad spectrum antibacterial agent for oral and intravenous administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. The chemical name is (-)-(S)-9-fluoro-2,3-dihydro-3-methyl- 10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6- carboxylic acid hemihydrate. Its empirical formula is C18H20FN3O4 ·½ H2O and its molecular weight is 370.38. Levofloxacin is a light yellowish-white to yellow-white crystal or crystalline powder. The molecule exists as a zwitterion at the pH conditions in the small intestine. The data demonstrate that from pH 0.6 to 5.8, the solubility of levofloxacin is essentially constant (approximately 100 mg/mL). Levofloxacin is considered soluble to freely soluble in this pH range, as defined by USP nomenclature. Above pH 5.8, the solubility increases rapidly to its maximum at pH 6.7 (272 mg/mL) and is considered freely soluble in this range. Above pH 6.7, the solubility decreases and reaches a minimum value (about 50 mg/mL) at a pH of approximately 6.9.
Levaquin has the following structural formula:
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