|
What is the most important information I should know about
fluvastatin?
|
|
• |
Rare cases of muscle problems and liver problems have been
associated with the use of fluvastatin and other similar medicines.
Contact your doctor immediately if you experience unexplained muscle
pain, tenderness, or weakness, especially if accompanied by a fever or
flulike symptoms or yellowing of the skin or eyes, abdominal pain,
unexplained fatigue, dark colored urine or pale colored stools. These
may be early symptoms of muscle or liver problems. |
|
• |
Do not take fluvastatin without first talking to your doctor if you
have liver disease. |
|
• |
Alcohol and fluvastatin can both be damaging to the liver. Alcohol
should be used only in moderation. Discuss the use of alcohol with your
doctor so that the potential for liver problems can be determined. |
|
• |
Do not take fluvastatin if you are pregnant, could become pregnant
during treatment, or if you are breast-feeding a baby. |
|
• |
Fluvastatin is an HMG CoA reductase inhibitor. Fluvastatin blocks
the production of cholesterol (a type of fat) in the body. |
|
• |
Fluvastatin is used to reduce the amounts of LDL (bad) cholesterol
and total cholesterol in your blood. Fluvastatin also reduces the
amounts of triglycerides (another type of fat) and apolipoprotein B (a
protein needed to make cholesterol) in your blood. These actions are
important in reducing the risk of hardening of the arteries, which can
lead to heart attacks, stroke, and peripheral vascular disease. |
|
• |
Fluvastatin may also be used for purposes other than those listed in
this medication guide. |
|
What should I discuss with my healthcare provider before taking
fluvastatin?
|
|
• |
Do not take fluvastatin without first talking to your doctor if you
have liver disease. |
|
• |
Before taking fluvastatin, tell your doctor if you |
| |
· |
drink alcoholic beverages, |
| |
· |
have a chronic muscular disease, or |
|
• |
You may not be able to take fluvastatin, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the
conditions listed above. |
|
• |
Fluvastatin is in the FDA pregnancy category X. This means that
fluvastatin is known to cause birth defects if it is taken during
pregnancy. Do not take fluvastatin if you are pregnant or could
become pregnant during treatment. |
|
• |
Fluvastatin passes into breast milk and may be harmful to a nursing
infant. Do not take fluvastatin without first talking to your doctor if
you are breast-feeding a baby. |
|
How should I take fluvastatin?
|
|
• |
Take fluvastatin exactly as directed by your doctor. If you do not
understand these directions, ask your pharmacist, nurse, or doctor to
explain them to you. |
|
• |
Take each dose with a full glass of water. |
|
• |
For the greatest effect, fluvastatin is usually taken at bedtime or
with an evening meal. Fluvastatin may also be taken twice daily. Follow
your doctor's directions. |
|
• |
Do not crush, chew, or break the extended-release tablets (Lescol
XL). Swallow them whole. |
|
• |
Your doctor may want to monitor your liver function with blood tests
before starting treatment with fluvastatin and at twelve weeks after
both the start of your treatment and any increase in dose. Depending on
the results of these tests, your doctor can determine how much
monitoring you will require. |
|
• |
Eat a low-fat, low-cholesterol diet. To realize beneficial effects
from fluvastatin, avoid fatty, high-cholesterol foods. |
|
• |
It is important to take fluvastatin regularly to get the most
benefit. |
|
• |
Do not stop taking fluvastatin without first talking to your doctor.
Fluvastatin may need to be taken on a long-term basis for the treatment
of high cholesterol. |
|
• |
Your doctor may want you to have blood tests or other medical
evaluations during treatment with fluvastatin to monitor progress and
side effects. |
|
• |
Store fluvastatin at room temperature away from moisture and heat. |
|
What happens if I miss a dose?
|
|
• |
Take the missed dose as soon as you remember. However, if it is
almost time for the next dose, skip the missed dose and take only the
next regularly scheduled dose. Do not take a double dose of this
medication. |
|
What happens if I overdose?
|
|
• |
Seek emergency medical attention if an overdose is suspected. |
|
• |
Symptoms of a fluvastatin overdose include nausea, diarrhea, stomach
distress, and
indigestion. |
|
What should I avoid while taking fluvastatin?
|
|
• |
Alcohol and fluvastatin can both be damaging to the liver. Alcohol
should be used only in moderation. Discuss the use of alcohol with your
doctor so that the potential for liver problems can be determined. |
|
What are the possible side effects of fluvastatin?
|
|
• |
Rare cases of muscle problems and liver problems have been
associated with the use of fluvastatin and other similar medicines.
Contact your doctor immediately if you experience unexplained muscle
pain, tenderness, or weakness, especially if accompanied by a fever or
flulike symptoms or yellowing of the skin or eyes, abdominal pain,
unexplained fatigue, dark colored urine or pale colored stools. These
may be early symptoms of muscle or liver problems. |
|
• |
If you experience any of the following serious side effects, stop
taking fluvastatin and seek emergency medical attention or contact your
doctor immediately: |
| |
· |
an allergic reaction (difficulty breathing; closing of the throat;
swelling of the lips, tongue, or face; or hives); |
| |
· |
decreased urine or rust-colored urine; or |
|
• |
Other, less serious side effects may be more likely to occur.
Continue to take fluvastatin and talk to your doctor if you experience |
| |
· |
gas, bloating, nausea, stomach upset, heartburn, abdominal pain,
constipation, or diarrhea; |
|
• |
Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
|
What other drugs will affect fluvastatin?
|
|
• |
Do not take fluvastatin without first talking to your doctor if you
are taking any of the following medicines: |
| |
· |
cyclosporine (Sandimmune, Neoral); |
| |
· |
gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate (Tricor); |
| |
· |
niacin (Nicolar, Nicobid, Slo-Niacin, others); |
| |
· |
erythromycin (E-Mycin, E.E.S., Ery-Tab, others) or clarithromycin (Biaxin); |
| |
· |
cholestyramine (Questran) or colestipol (Colestid); |
| |
· |
rifampin (Rifadin, Rimactane); |
| |
· |
digoxin (Lanoxin, Lanoxicaps); or |
|
• |
You may not be able to take fluvastatin, or you may require a dosage
adjustment or special monitoring during treatment if you are taking any
of the medicines listed above. |
|
• |
Drugs other than those listed here may also interact with
fluvastatin. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines, including vitamins, minerals,
and herbal products. |
|
Where can I get more information?
|
|
• |
Your pharmacist has additional information about fluvastatin written
for health professionals that you may read. |
|
• |
Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
|
• |
Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2005 Cerner Multum, Inc. Version: 9.01. Revision date: 10/
10/ 05. |