Latanoprost is used to reduce elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension by increasing the amount of fluid that drains from the eye.
Use Latanoprost ophthalmic eye drops exactly as directed by your doctor. It is usually used once a day, one drop in the affected eye in the evening. Wash your hands before and after using the eye drops. It contains a preservative, so do not wear soft contact lenses when applying this medication. You can be inserted 15 minutes after application of the drops. It is important not to touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection. Do not use any eye drop that is discolored or has particles in it. If you are using another type of eye medication, apply it after 5 minutes before after a dose of latanoprost. Store latanoprost ophthalmic in the refrigerator before the opening the bottle. If the bottle is opened, it can be stored at room temperature of up to 77 degrees Fahrenheit. Keep the bottle capped.
To apply the latanoprost eye drops: Tilt the head back slightly and pull down on your lower eyelid. Position the dropper above the eye. Steady the hand holding the bottle by placing your thumb against your brow or the bridge of your nose. Look up and away from the dropper. Press or lightly tap the side of the bottle to allow only a single drop of medicine to fall into the pocket formed by the lower eyelid. Do not allow the dropper to touch the eye, eyelid, or hands. Instill the number of drops prescribed by your doctor. Close your eye for approximately 2 to 3 minutes.
Latanoprost ophthalmic overdose symptoms include burning, irritation, and redness of the eyes. Seek medical attention if you have these symptoms.
Possible side effects include: itching, redness, or discharge from the eyes. It can also cause the iris to change. The amount of brown pigment in the eyes may increase; however, this color change only occurs in the eye being treated.
If you are taking over-the-counter medicines including vitamins, minerals, and herbal products, talk to your doctor and pharmacist before taking any prescription.
Tell your doctor about your medical history before using this medication. Latanoprost ophthalmic is in the FDA pregnancy category C, meaning that it is not known whether it will be harmful to an unborn baby. If you are pregnant, do not use latanoprost ophthalmic without first talking to your doctor. It is not known whether it can pass into breast milk; therefore, do not use latanoprost without first talking to your doctor if you are breast feeding a baby.
Latanoprost is a colorless to slightly yellow oil which is very soluble in acetonitrile and freely soluble in acetone, ethanol, ethyl acetate, isopropanol, methanol, and octanol. It is practically insoluble in water. Xalatan sterile ophthalmic solution is supplied as sterile, isotonic, buffered aqueous solution of latanoprost with a pH of approximately 6.7 and an osmolality of approximately 267 mOsmol/kg. Each ml of Xalatan contains 50 mcg of latanoprost. Benzalkonium chloride, 0.02% is added as a preservative. Inactive Ingredients: Sodium chloride, sodium dihydrogen phosphate monohydrate, disodium hydrogen phosphate anhydrous, and water for injection. One drop contains approximately 1.5 mcg of latanoprost.
Latanoprost has the following structural formula: