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What is the most important information I should know about
lamotrigine?
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In rare cases, lamotrigine has been associated with severe
and/ or life-threatening rashes and hypersensitivity reactions. Seek
emergency medical attention or contact your doctor immediately if you
develop any skin rash; fever; hives; swelling of the lips, tongue, or
face; sores in the mouth or around the eyes; or swollen lymph glands. |
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Seek emergency medical attention or contact your doctor
immediately if you experience increasing frequency or worsening of
seizures during treatment with lamotrigine. |
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Do not stop taking lamotrigine without first talking to your
doctor, even if you feel better. It is important to continue taking
lamotrigine to prevent symptoms from recurring. Stopping lamotrigine
suddenly may result in increased seizure frequency or a return of
symptoms of bipolar disorder. If the medication needs to be stopped,
your doctor may need to lower the dosage gradually. |
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Carry or wear a medical identification tag to let others know
that you are taking this medicine in the case of an emergency. |
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Lamotrigine may cause drowsiness, dizziness, blurred vision,
or poor coordination. Do not drive, operate dangerous machinery, or
perform other hazardous activities until you know how lamotrigine
affects you. If you experience drowsiness, dizziness, blurred vision, or
poor coordination, avoid these activities. |
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The exact way that lamotrigine works is unknown. However, it
is believed that lamotrigine affects chemicals in the brain involved in
seizures and in bipolar disorder. |
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Lamotrigine is used alone or in combination with other
medications in the treatment of seizures. Lamotrigine is also used in
the treatment of bipolar disorder. |
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Lamotrigine may also be used for purposes other than those
listed in this medication guide. |
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What should I discuss with my healthcare provider before taking
lamotrigine?
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In rare cases, lamotrigine has been associated with severe
and/ or life-threatening rashes and hypersensitivity reactions. Seek
emergency medical attention or contact your doctor immediately if you
develop any skin rash; fever; hives; swelling of the lips, tongue, or
face; sores in the mouth or around the eyes; or swollen lymph glands. |
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Before taking lamotrigine, tell your doctor if you have
heart, liver, or kidney disease or other serious medical problems. You
may not be able to take lamotrigine, or you may require a dosage
adjustment or special monitoring during treatment. |
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Do not start or stop using birth control pills or other
female hormonal products until you have consulted your doctor. Tell your
doctor as soon as possible if you experience changes in your menstrual
pattern (e.g., break-through bleeding) while taking lamotrigine and
birth control pills or other female hormonal products. |
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Lamotrigine is in the FDA pregnancy category C. This means
that it is not known whether lamotrigine will be harmful to an unborn
baby. Do not take this medication without first talking to your doctor
if you are pregnant or could become pregnant during treatment. |
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Lamotrigine passes into breast milk and may affect a nursing
infant. Do not take lamotrigine without first talking to your doctor if
you are breast-feeding a baby. |
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How should I take lamotrigine?
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Take lamotrigine exactly as directed by your doctor. If you
do not understand these directions, ask your pharmacist, nurse, or
doctor to explain them to you. |
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Take each oral dose of lamotrigine with a full glass of
water. |
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Swallow the regular (nonchewable) lamotrigine tablets whole.
The tablets may have a very bitter taste if chewed, crushed, or broken. |
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The chewable, dispersible tablets can be swallowed whole,
chewed, or mixed in water or diluted fruit juice. If you chew these
tablets, drink a small amount of water or diluted fruit juice to aid in
swallowing. To disperse these tablets, add the tablet(s) to a small
amount of liquid (1 teaspoon or enough to cover the medication) in a
glass or spoon. Approximately 1 minute later, when the tablet is
completely dispersed, mix the solution and take the entire amount
immediately. |
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Lamotrigine can be taken with or without food. |
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It is important to take lamotrigine regularly to get the
most benefit. |
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The dose of lamotrigine must be increased slowly. It may be
several weeks or months before the optimal dose can be determined. |
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Do not stop taking lamotrigine without first talking to your
doctor, even if you feel better. It is important to continue taking
lamotrigine to prevent symptoms from recurring. Stopping lamotrigine
suddenly may result in increased seizure frequency or a return of
symptoms of bipolar disorder. If the medication needs to be stopped,
your doctor may need to lower the dosage gradually. |
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If treatment with lamotrigine is stopped for any reason,
contact your doctor before restarting the medication. A lower dose may
be needed to prevent side effects from occurring. |
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Do not take more of this medication than is prescribed by
your doctor. |
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Your doctor may want you to have
blood tests or other medical evaluations during treatment with
lamotrigine to monitor progress and side effects. |
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Carry or wear a medical identification tag to let others
know that you are taking this medicine in the case of an emergency. |
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Store this medication at room temperature away from light
and moisture. |
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What happens if I miss a dose?
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Take the missed dose as soon as you remember. However, if it
is almost time for the next dose, skip the dose you missed and take only
the next regularly scheduled dose. Do not take a double dose of
this medication. |
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What happens if I overdose?
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Seek emergency medical treatment. |
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Symptoms of a lamotrigine overdose include dizziness,
drowsiness, headache, increased seizures, and unconsciousness. |
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What should I avoid while taking lamotrigine?
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Lamotrigine may cause drowsiness, dizziness, blurred vision,
or poor coordination. Do not drive, operate dangerous machinery, or
perform other hazardous activities until you know how lamotrigine
affects you. If you experience drowsiness, dizziness, blurred vision, or
poor coordination, avoid these activities. |
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What are the possible side effects of lamotrigine?
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• |
In rare cases, lamotrigine has been associated with severe
and/ or life-threatening rashes and hypersensitivity reactions. Seek
emergency medical attention or contact your doctor immediately if you
develop any skin rash; fever; hives; swelling of the lips, tongue, or
face; sores in the mouth or around the eyes; or swollen lymph glands. |
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• |
Seek emergency medical attention or contact your doctor
immediately if you experience increasing frequency or worsening of
seizures during treatment with lamotrigine. |
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Other, less serious side effects may be more likely to occur.
Continue to take lamotrigine and talk to your doctor if you experience |
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dizziness or drowsiness; |
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blurred or double vision; |
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Side effects other than those listed here may also occur.
Talk to your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect lamotrigine?
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Lamotrigine interacts with many other drugs used to treat
seizures. Before taking lamotrigine, tell your doctor about all
other medications you are taking. You may require a dosage adjustment or
special monitoring during treatment if you are taking lamotrigine alone
or with other medications to treat seizures. Continue to take all
medications prescribed to treat seizures exactly as directed. |
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Birth control pills may decrease the amount of lamotrigine
in the body. A dosage adjustment may be necessary if birth control pills
are started or stopped during treatment with lamotrigine. |
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Lamotrigine may increase the effects of other drugs that cause
drowsiness, including antidepressants, alcohol, antihistamines,
sedatives (used to treat insomnia), pain relievers, anxiety medicines,
and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may
occur if lamotrigine is taken with any of these medications. |
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Drugs other than those listed here may also interact with
lamotrigine. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines, including vitamins, minerals,
and herbal products. |
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Where can I get more information?
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Your pharmacist has additional information about lamotrigine written
for health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
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Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2005 Cerner Multum, Inc. Version: 9.01. Revision date: 2/
2/ 05. |