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What is the most important information I should know about
lamotrigine?
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In rare cases, lamotrigine has been associated with severe and/ or
life-threatening rashes and hypersensitivity reactions. Seek emergency
medical attention or contact your doctor immediately if you develop any
skin rash; fever; hives; swelling of the lips, tongue, or face; sores in
the mouth or around the eyes; or swollen lymph glands. |
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Seek emergency medical attention or contact your doctor immediately
if you experience increasing frequency or worsening of seizures during
treatment with lamotrigine. |
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Do not stop taking lamotrigine without first talking to your doctor,
even if you feel better. It is important to continue taking lamotrigine
to prevent symptoms from recurring. Stopping lamotrigine suddenly may
result in increased seizure frequency or a return of symptoms of bipolar
disorder. If the medication needs to be stopped, your doctor may need to
lower the dosage gradually. |
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Carry or wear a medical identification tag to let others know that
you are taking this medicine in the case of an emergency. |
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Lamotrigine may cause drowsiness, dizziness, blurred vision, or poor
coordination. Do not drive, operate dangerous machinery, or perform
other hazardous activities until you know how lamotrigine affects you.
If you experience drowsiness, dizziness, blurred vision, or poor
coordination, avoid these activities. |
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The exact way that lamotrigine works is unknown. However, it is
believed that lamotrigine affects chemicals in the brain involved in
seizures and in bipolar disorder. |
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Lamotrigine is used alone or in combination with other medications
in the treatment of seizures. Lamotrigine is also used in the treatment
of bipolar disorder. |
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Lamotrigine may also be used for purposes other than those listed in
this medication guide. |
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What should I discuss with my healthcare provider before taking
lamotrigine?
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• |
In rare cases, lamotrigine has been associated with severe and/ or
life-threatening rashes and hypersensitivity reactions. Seek emergency
medical attention or contact your doctor immediately if you develop any
skin rash; fever; hives; swelling of the lips, tongue, or face; sores in
the mouth or around the eyes; or swollen lymph glands. |
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Before taking lamotrigine, tell your doctor if you have heart, liver,
or kidney disease or other serious medical problems. You may not be able
to take lamotrigine, or you may require a dosage adjustment or special
monitoring during treatment. |
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Do not start or stop using birth control pills or other female
hormonal products until you have consulted your doctor. Tell your doctor
as soon as possible if you experience changes in your menstrual pattern
(e.g., break-through bleeding) while taking lamotrigine and birth
control pills or other female hormonal products. |
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Lamotrigine is in the FDA pregnancy category C. This means that it
is not known whether lamotrigine will be harmful to an unborn baby. Do
not take this medication without first talking to your doctor if you are
pregnant or could become pregnant during treatment. |
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Lamotrigine passes into breast milk and may affect a nursing infant.
Do not take lamotrigine without first talking to your doctor if you are
breast-feeding a baby. |
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How should I take lamotrigine?
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Take lamotrigine exactly as directed by your doctor. If you do not
understand these directions, ask your pharmacist, nurse, or doctor to
explain them to you. |
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Take each oral dose of lamotrigine with a full glass of water. |
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Swallow the regular (nonchewable) lamotrigine tablets whole. The
tablets may have a very bitter taste if chewed, crushed, or broken. |
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The chewable, dispersible tablets can be swallowed whole, chewed, or
mixed in water or diluted fruit juice. If you chew these tablets, drink
a small amount of water or diluted fruit juice to aid in swallowing. To
disperse these tablets, add the tablet(s) to a small amount of liquid (1
teaspoon or enough to cover the medication) in a glass or spoon.
Approximately 1 minute later, when the tablet is completely dispersed,
mix the solution and take the entire amount immediately. |
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Lamotrigine can be taken with or without food. |
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It is important to take lamotrigine regularly to get the most
benefit. |
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The dose of lamotrigine must be increased slowly. It may be several
weeks or months before the optimal dose can be determined. |
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Do not stop taking lamotrigine without first talking to your doctor,
even if you feel better. It is important to continue taking lamotrigine
to prevent symptoms from recurring. Stopping lamotrigine suddenly may
result in increased seizure frequency or a return of symptoms of bipolar
disorder. If the medication needs to be stopped, your doctor may need to
lower the dosage gradually. |
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If treatment with lamotrigine is stopped for any reason, contact
your doctor before restarting the medication. A lower dose may be needed
to prevent side effects from occurring. |
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Do not take more of this medication than is prescribed by your
doctor. |
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Your doctor may want you to have blood tests or other medical
evaluations during treatment with lamotrigine to monitor progress and
side effects. |
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Carry or wear a medical identification tag to let others know that
you are taking this medicine in the case of an emergency. |
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Store this medication at room temperature away from light and
moisture. |
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What happens if I miss a dose?
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Take the missed dose as soon as you remember. However, if it is
almost time for the next dose, skip the dose you missed and take only
the next regularly scheduled dose. Do not take a double dose of
this medication. |
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What happens if I overdose?
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Seek emergency medical treatment. |
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Symptoms of a lamotrigine overdose include dizziness, drowsiness,
headache, increased seizures, and unconsciousness. |
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What should I avoid while taking lamotrigine?
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Lamotrigine may cause drowsiness, dizziness, blurred vision, or poor
coordination. Do not drive, operate dangerous machinery, or perform
other hazardous activities until you know how lamotrigine affects you.
If you experience drowsiness, dizziness, blurred vision, or poor
coordination, avoid these activities. |
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What are the possible side effects of lamotrigine?
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• |
In rare cases, lamotrigine has been associated with severe and/ or
life-threatening rashes and hypersensitivity reactions. Seek emergency
medical attention or contact your doctor immediately if you develop any
skin rash; fever; hives; swelling of the lips, tongue, or face; sores in
the mouth or around the eyes; or swollen lymph glands. |
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• |
Seek emergency medical attention or contact your doctor immediately
if you experience increasing frequency or worsening of seizures during
treatment with lamotrigine. |
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Other, less serious side effects may be more likely to occur.
Continue to take lamotrigine and talk to your doctor if you experience |
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dizziness or drowsiness; |
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blurred or double vision; |
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Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect lamotrigine?
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Lamotrigine interacts with many other drugs used to treat seizures.
Before taking lamotrigine, tell your doctor about all other
medications you are taking. You may require a dosage adjustment or
special monitoring during treatment if you are taking lamotrigine alone
or with other medications to treat seizures. Continue to take all
medications prescribed to treat seizures exactly as directed. |
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Birth control pills may decrease the amount of lamotrigine in the
body. A dosage adjustment may be necessary if birth control pills are
started or stopped during treatment with lamotrigine. |
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Lamotrigine may increase the effects of other drugs that cause
drowsiness, including antidepressants, alcohol, antihistamines,
sedatives (used to treat insomnia), pain relievers, anxiety medicines,
and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may
occur if lamotrigine is taken with any of these medications. |
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Drugs other than those listed here may also interact with
lamotrigine. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines, including vitamins, minerals,
and herbal products. |
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Where can I get more information?
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Your pharmacist has additional information about lamotrigine written
for health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
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Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2005 Cerner Multum, Inc. Version: 9.01. Revision date: 2/
2/ 05. |
