Insulin is one of many hormones that occur naturally in the body. After eating, insulin works by causing sugar to leave the blood into our cells to make fat, sugar, and protein, and by helping us use the fat, sugar, and protein that we have stored. If your body is not making the proper amount of insulin, it must be supplemented by regular injections. Insulin may be from beef or pork pancreas glands, or semi-synthetic or recombinant DNA created insulin called human insulin.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as your insulin dosage will have to be adjusted. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and be especially careful to not forget a dose.
Tell your doctor immediately if any of the following side effects occur: convulsions or unconsciousness.
Talk with your doctor as soon as possible if any of the following side effects occur: low blood sugar (mild), including anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, unusual tiredness or weakness; weight gain; depressed skin at the place of injection; swelling of face, fingers, feet, or ankles; or thickening of the skin at the place of injection.
NovoLog (insulin aspart [rDNA origin] injection) is a human insulin analog that is a rapid-acting, parenteral blood glucose-lowering agent. NovoLog is homologous with regular human insulin with the exception of a single substitution of the amino acid proline by aspartic acid in position B28, and is produced by recombinant DNA technology utilizing Saccharomyces cerevisiae (baker's yeast) as the production organism. Insulin aspart has the empirical formula C256H381N65079S6 and a molecular weight of 5825.8. NovoLog is a sterile, aqueous, clear, and colorless solution, that contains insulin aspart (B28 asp regular human insulin analog) 100 Units/mL, glycerin 16 mg/mL, phenol 1.50 mg/mL, metacresol 1.72 mg/mL, zinc 19.6 µg/mL, disodium hydrogen phosphate dihydrate 1.25 mg/mL, and sodium chloride 0.58 mg/mL. NovoLog has a pH of 7.2-7.6. Hydrochloric acid 10% and/or sodium hydroxide 10% may be added to adjust pH.
Insulin has the following structural formula: