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Fluoxetine Fluoxetine review
Pharmacy and Drugs

     .: Prescription

Fluoxetine is used as treatment for major depressive disorder, treatment of binge-eating and vomiting in patients with moderate-to-severe bulimia nervosa; obsessive-compulsive disorder (OCD); premenstrual dysphoric disorder (PMDD); panic disorder with or without agoraphobia.

Fluoxetine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors. It affects chemicals in the brain that may become unbalanced causing depression, panic, anxiety, or obsessive-compulsive symptoms.

Fluoxetine should be taken exactly as it was prescribed for you. It should not be taken in larger amounts or taken for longer than recommended by your doctor. Do not break, chew, or open an extended-release capsule. It should be swallowed whole. It is specially made to release medicine slowly in the body. It may take 4 weeks or longer before you start feeling better. Do not stop using fluoxetine without first talking to your doctor. You ay have unpleasant side effects if you stop taking this medication suddenly.

Possible side effects of fluoxetine include: signs of an allergic reaction; skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Get emergency medical help if you have any of these. Mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania, thoughts of suicide or hurting yourself are the other side effects. Contact your doctor promptly. Other less serious side effects include: feeling anxious, nervous, restless, or unable to sit still, drowsiness, dizziness, weakness, sleep problems, runny nose, sore throat, headache, flu symptoms, nausea, diarrhea, changes in appetite, weight changes, decreased sex drive, impotence, or difficulty having an orgasm, or dry mouth and increased sweating.

Taking any medicine for pain, arthritis, fever or swelling such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others with fluoxetine may cause you to bruise or bleed easily.

Other drugs that can affect fluoxetine include: alprazolam (Xanax); clozapine (Clozaril, Fazaclo); digitoxin (Crystodigin); flecainide (Tambocor); haloperidol (Haldol); seizure medication such as phenytoin (Dilantin) or carbamazepine (Tegretol); tryptophan (also called L-tryptophan); vinblastine (Velban); a blood thinner such as warfarin (Coumadin); almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or any other antidepressants such as amitriptyline (Elavil), citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), or sertraline (Zoloft). If you are using any of these drugs, you may not be able to use fluoxetine, or you may need dosage adjustments or special tests during treatment.

Fluoxetine hydrochloride is a white to off-white crystalline solid with a solubility of 14 mg/mL in water. Each Pulvule contains fluoxetine hydrochloride equivalent to 10 mg (32.3 mmol), 20 mg (64.7 mmol), or 40 mg (129.3 mmol) of fluoxetine. The Pulvules also contain starch, gelatin, silicone, titanium dioxide, iron oxide, and other inactive ingredients. The 10- and 20-mg Pulvules also contain FD&C Blue No. 1, and the 40-mg Pulvule also contains FD&C Blue No. 1 and FD&C Yellow No. 6. Each tablet contains fluoxetine hydrochloride equivalent to 10 mg (32.3 mmol) of fluoxetine. The tablets also contain microcrystalline cellulose, magnesium stearate, crospovidone, hypromellose, titanium dioxide, polyethylene glycol, and yellow iron oxide. In addition to the above ingredients, the 10-mg tablet contains FD&C Blue No. 1 aluminum lake and polysorbate 80. The oral solution contains fluoxetine hydrochloride equivalent to 20 mg/5 mL (64.7 mmol) of fluoxetine. It also contains alcohol 0.23%, benzoic acid, flavoring agent, glycerin, purified water, and sucrose.

Fluoxetine has the following structural formula:

Chemical structure of Fluoxetine
Brand name: Prozac :: Sarafem

Similar drugs: Zoloft :: Anafranil :: Temazepam

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