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    Fluconazole
Fluconazole Fluconazole review
by
Pharmacy and Drugs


     .: Prescription

Fluconazole is an antifungal medication. It is used to treat fungal infections. It is used to treat yeast infections of the mouth, throat, and esophagus; vaginal yeast infections; fungal urinary tract infections; pneumonia caused by yeast; and fungal infections throughout the whole body and in the blood. Fluconazole is also used to prevent fungal infections from occurring in people with suppressed immune systems such as cancer chemotherapy patients, organ transplant patients, and AIDS patients. Fluconazole may also be used for purposes other than those listed in this medication guide.

Take fluconazole exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. A single dose of this medication is often used to treat vaginal yeast infections. In multiple-dose therapy, a double dose of fluconazole is often taken on the first day of treatment to quickly get the proper amount of medicine into the body. Follow your doctor's directions. Shake the suspension well before measuring a dose. To ensure that you get the correct dose, measure the suspension using a dose-measuring spoon, cup, or dropper, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. It is important to take fluconazole regularly to get the most benefit. Store the tablets at room temperature away from moisture and heat. The suspension can be stored at room temperature or in the refrigerator. Do not let it freeze. Throw away any unused suspension after 14 days.

If you experience any of the following serious side effects, stop taking fluconazole and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); liver damage (pale stools, yellowing of the skin or eyes, abdominal pain, unusual fatigue, or dark urine); or a rash.

Other, less serious side effects may be more likely to occur. If you experience any of the following side effects, continue taking fluconazole and talk to your doctor: nausea, vomiting, or abdominal pain; diarrhea; headache; dizziness; fatigue; or itching.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Symptoms of a fluconazole overdose include confusion, hallucinations, paranoia, decreased movement, decreased breathing, tearing eyes, drooling, urinary incontinence, seizures, and death.

Do not take fluconazole if you are taking cisapride (Propulsid). Combined with cisapride (Propulsid), fluconazole could cause serious, even fatal, heart problems.

Before taking fluconazole, tell your doctor if you are taking any other medicines, especially any of the following: an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others; cyclosporine (Sandimmune, Neoral); cisapride (Propulsid); a benzodiazepine such as diazepam (Valium), lorazepam (Ativan), alprazolam (Xanax), estazolam (ProSom) and others; tacrolimus ((Prograf); rifabutin (Mycobutin) or rifampin (Rifadin, Rimactane); or theophylline (Theo-Dur, Theolair, Theochron, Elixophyllin, Slo-Phyllin, others); or astemizole (Hismanal).

Fluconazole is designated chemically as 2,4-difluoro-a,a1-bis(1H-1,2,4-triazol-1-ylmethyl) benzyl alcohol with an empirical formula of C13H12F2N6O and molecular weight 306.3. Diflucan Tablets: Contain 50, 100, 150, or 200 mg of fluconazole and the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, povidone, croscarmellose sodium, FD&C red no. 40 aluminum lake dye, and magnesium stearate. Diflucan for Oral Suspension: Contains 350 mg or 1400 mg of fluconazole and the following inactive ingredients: sucrose, sodium citrate dihydrate, citric acid anhydrous, sodium benzoate, titanium dioxide, colloidal silicon dioxide, xanthan gum and natural orange flavor. After reconstitution with 24 ml of distilled water or Purified Water (USP), each ml of reconstituted suspension contains 10 mg or 40 mg of fluconazole. Diflucan Injection: It is an iso-osmotic, sterile, nonpyrogenic solution of fluconazole in a sodium chloride or dextrose diluent. Each ml contains 2 mg of fluconazole and 9 mg of sodium chloride or 56 mg of dextrose, hydrous. The pH ranges from 4.0 to 8.0 in the sodium chloride diluent and from 3.5 to 6.5 in the dextrose diluent. Injection volumes of 100 ml and 200 ml are packaged in glass and in Viaflex Plus plastic containers.

Fluconazole has the following structural formula:

Chemical structure of Fluconazole
Brand name: Diflucan

Similar drugs: Loratadine :: Cefprozil :: Cefzil

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