Flonase, also called Fluticasone, belongs to the family of medicines known as Corticosteroids, which are part of the family of steroids. Flonase is sprayed into the nose to help relieve the stuffy or runny nose, irritation, sneezing, and discomfort of hay fever, or other nasal allergies.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Tell your doctor as soon as possible if any of the following side effects occur: bloody mucus or unexplained nosebleeds; cough; headache; nausea; shortness of breath; vomiting; diarrhea; dizziness; excessive mucus; fever; general aches and pains; loss of appetite; stomach pain; weakness; runny nose; or white patches inside nose or throat.
Fluticasone propionate, the active component of FLONASE Nasal Spray, is a synthetic corticosteroid having the chemical name S-(fluoromethyl)6a,9-difluoro-11ß-17-dihydroxy-16a- methyl-3-oxoandrosta- 1,4-diene-17ß-carbothioate, 17-propionate. Fluticasone propionate is a white to off-white powder with a molecular weight of 500.6, and the empirical formula is C25H31F3O5S. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol. FLONASE Nasal Spray, 50 mcg is an aqueous suspension of microfine fluticasone propionate for topical administration to the nasal mucosa by means of a metering, atomizing spray pump. FLONASE Nasal Spray also contains microcrystalline cellulose and carboxymethylcellulose sodium, dextrose, 0.02% w/w benzalkonium chloride, polysorbate 80, and 0.25% w/w phenylethyl alcohol, and has a pH between 5 and 7.
Flonase has the following structural formula: