Femara, also called Letrozole, is used to treat certain types of breast cancer in women. Hormones that occur naturally in the body can increase the growth of some breast cancers. Femara works by decreasing the amounts of these hormones in the body. This medicine is only for women who have already stopped menstruating.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Femara without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Stop taking Femara and get emergency help immediately if any of the following side effects occur: shortness of breath; chest pain; continuing or severe nervousness; cough; dizziness or lightheadedness; fainting; fast heartbeat; heart attack; increased sweating; nausea; pain in chest, groin, or legs, especially the calves; severe, sudden headache; slurred speech; severe and sudden, unexplained shortness of breath; sudden loss of coordination; sudden, severe weakness or numbness in arm or leg; or vision changes.
Femara (letrozole tablets) for oral administration contain 2.5 mg of letrozole, a nonsteroidal aromatase inhibitor (inhibitor of estrogen synthesis). It is chemically described as 4,4'-(1H-1,2,4 -Triazol-1-ylmethylene) dibenzonitrile. Letrozole is a white to yellowish crystalline powder, practically odorless, freely soluble in dichloromethane, slightly soluble in ethanol, and practically insoluble in water. It has a molecular weight of 285.31, empirical formula C17H11N5 and a melting range of 184o C-185o C.
Femara (letrozole tablets) is available as 2.5 mg tablets for oral administration.
Femara has the following structural formula: