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Elavil
This page contains drug information on Elavil.
The information provided includes the following:
- what is Elavil
- the possible side effects of Elavil
- what happens if you miss a dose of Elavil
- what happens if you overdose with Elavil
- the most important information about Elavil
- how to use Elavil
- other drugs that may affect Elavil
- what to avoid while using Elavil
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Generic Name: amitriptyline (a mee TRIP ti leen)
Brand Names:
Elavil, Endep, Vanatrip |
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What is the most important information I should know about
amitriptyline?
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Do not use this medication if you are allergic to amitriptyline, or
if you have recently had a heart attack. |
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Do not use amitriptyline if you have taken cisapride (Propulsid) or
used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil),
rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate)
within the past 14 days. |
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You may have an increased risk of suicidal thoughts or behavior at
the start of treatment with an antidepressant medication, especially if
you are under 18 years old. While you are taking this medication you
will need to be monitored for worsening symptoms of depression and/ or
suicidal thoughts during the first weeks of treatment, or whenever your
dose is changed. Your doctor will need to check you at regular visits
for at least the first 12 weeks of treatment. |
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Contact your doctor promptly if you have any of the following side
effects, especially if they are new symptoms or if they get worse: mood
changes, anxiety, panic attacks, trouble sleeping, irritability,
agitation, aggressiveness, severe restlessness, mania (mental and/ or
physical hyperactivity), thoughts of suicide or hurting yourself. |
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Amitriptyline is in a group of drugs called tricyclic
antidepressants. Amitriptyline affects chemicals in the brain that may
become unbalanced. |
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Amitriptyline is used to treat symptoms of depression. |
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Amitriptyline may also be used for purposes other than those listed
in this medication guide. |
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What should I discuss with my healthcare provider before taking
amitriptyline?
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Do not use this medication if you are allergic to amitriptyline, or
if you have recently had a heart attack. |
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Do not use amitriptyline if you have taken cisapride (Propulsid) or
used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil),
rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate)
within the past 14 days. Serious, life-threatening side effects can
occur if you take amitriptyline before the MAO inhibitor has cleared
from your body. |
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Before taking amitriptyline, tell your doctor if you are allergic to
any drugs, or if you have: |
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a history of heart attack, stroke, or seizures; |
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bipolar disorder (manic-depression); |
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schizophrenia or other mental illness; |
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diabetes (amitriptyline may raise or lower blood sugar); |
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problems with urination. |
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If you have any of these conditions, you may not be able to use
amitriptyline, or you may need a dosage adjustment or special tests
during treatment. |
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You may have an increased risk of suicidal thoughts or behavior at
the start of treatment with an antidepressant medication, especially if
you are under 18 years old. While you are taking amitriptyline, you will
need to be monitored for worsening symptoms of depression and/ or
suicidal thoughts during the first weeks of treatment, or whenever your
dose is changed. |
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In addition to you watching for changes in your own symptoms, your
family or other caregivers should be alert to changes in your mood or
symptoms. Your doctor will need to check you at regular visits for at
least the first 12 weeks of treatment. |
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Contact your doctor promptly if you have any of the following side
effects, especially if they are new symptoms or if they get worse: mood
changes, anxiety, panic attacks, trouble sleeping, irritability,
agitation, aggressiveness, severe restlessness, mania (mental and/ or
physical hyperactivity), thoughts of suicide or hurting yourself. |
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FDA pregnancy category C. This medication may be harmful to an
unborn baby. Tell your doctor if you are pregnant or plan to become
pregnant during treatment. |
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Amitriptyline can pass into breast milk and may harm a nursing baby.
Do not use this medication without telling your doctor if you are
breast-feeding a baby. |
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Older adults may be more likely to have side effects from this
medicine. |
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Do not give this medication to a child younger than 12 years old. |
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How should I take amitriptyline?
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Take this medication exactly as it was prescribed for you. Do not
take the medication in larger amounts, or take it for longer than
recommended by your doctor. Your doctor may occasionally change your
dose to make sure you get the best results from this medication. Follow
the directions on your prescription label. |
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If you need to have any type of surgery, tell the surgeon ahead of
time that you are taking amitriptyline. You may need to stop using the
medicine for a short time. |
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Do not stop using amitriptyline without first talking to your doctor.
You may need to use less and less before you stop the medication
completely. Stopping this medication suddenly could cause you to have
unpleasant side effects. |
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It may take up to 4 weeks of using this medicine before your
symptoms improve. For best results, keep using the medication as
directed. Talk with your doctor if your symptoms do not improve after 4
weeks of treatment. |
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Store amitriptyline at room temperature away from moisture and heat. |
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What happens if I miss a dose?
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Take the missed dose as soon as you remember. If it is almost time
for your next dose, skip the missed dose and take the medicine at the
next regularly scheduled time. Do not take extra medicine to make
up the missed dose. |
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What happens if I overdose?
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Seek emergency medical attention if you think you have used too much
of this medicine. An overdose of amitriptyline can be fatal. |
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Symptoms of an amitriptyline overdose may include uneven heartbeats,
extreme drowsiness, confusion, agitation, vomiting, blurred vision,
feeling hot or cold, sweating, muscle stiffness, feeling light-headed,
fainting, seizure (convulsions), or coma. |
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What should I avoid while taking amitriptyline?
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Avoid drinking alcohol. It can cause dangerous side effects when
taken together with amitriptyline. |
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Avoid using other medicines that make you sleepy (such as cold
medicine, pain medication, muscle relaxers, medicine for seizures, or
other antidepressants). They can add to sleepiness caused by
amitriptyline. |
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Grapefruit and grapefruit juice may interact with amitriptyline.
Discuss the use of grapefruit products with your doctor before
increasing or decreasing the amount of grapefruit products in your diet. |
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Amitriptyline can cause side effects that may impair your thinking
or reactions. Be careful if you drive or do anything that requires you
to be awake and alert. |
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Avoid exposure to sunlight or artificial UV rays (sunlamps or
tanning beds). Amitriptyline can make your skin more sensitive to
sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and
wear protective clothing if you must be out in the sun. |
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What are the possible side effects of amitriptyline?
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Get emergency medical help if you have any of these signs of an
allergic reaction: hives; difficulty breathing; swelling of your
face, lips, tongue, or throat. |
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Call your doctor at once if you have any of these serious side
effects: |
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fast, pounding, or uneven heart rate; |
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chest pain or heavy feeling, pain spreading to the arm or shoulder,
nausea, sweating, general ill feeling; |
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sudden numbness or weakness, especially on one side of the body; |
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sudden headache, confusion, problems with vision, speech, or balance; |
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confusion, hallucinations, or seizures (convulsions); |
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restless muscle movements in your eyes, tongue, jaw, or neck; |
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uncontrollable shaking or tremor; |
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skin rash, severe tingling, numbness, pain, muscle weakness; |
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easy bruising or bleeding; |
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extreme thirst with headache, nausea, vomiting, and weakness; |
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feeling light-headed, fainting; or |
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urinating less than usual or not at all. |
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Less serious side effects may be more likely to occur, such as: |
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nausea, vomiting, constipation, diarrhea, loss of appetite; |
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dry mouth, unpleasant taste; |
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numbness or tingly feeling; |
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feeling anxious, dizzy, drowsy, or tired; |
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sleep problems (insomnia), nightmares; |
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blurred vision, headache, ringing in your ears; |
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breast swelling (in men or women); or |
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decreased sex drive, impotence, or difficulty having an orgasm. |
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Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect amitriptyline?
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Before taking amitriptyline, tell your doctor if you have used an
"SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa),
escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox),
paroxetine (Paxil), or sertraline (Zoloft). |
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Before taking amitriptyline, tell your doctor if you are currently
using any of the following drugs: |
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guanethidine (Ismelin); |
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disulfiram (Antabuse); or |
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heart rhythm medications such as flecainide (Tambocor), propafenone
(Rhythmol), or quinidine (Cardioquin, Quinidex, Quinaglute). |
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If you are using any of these drugs, you may not be able to use
amitriptyline, or you may need dosage adjustments or special tests
during treatment. |
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There are many other medicines that can interact with
amitriptyline. Tell your doctor about all the prescription and
over-the-counter medications you use. This includes vitamins, minerals,
herbal products, and drugs prescribed by other doctors. Do not start
using a new medication without telling your doctor. Keep a list with you
of all the medicines you use and show this list to any doctor or other
healthcare provider who treats you. |
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Where can I get more information?
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Your pharmacist has information about amitriptyline written for
health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
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Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2006 Cerner Multum, Inc. Version: 6.01. Revision date: 9/
19/ 06. |
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