Diovan (Valsartan) belongs to the class of medicines called Angiotensin II Inhibitors, and is an Antihypertensive. It is used to treat high blood pressure, heart failure, and can reduce the need for hospitalization from heart failure. Diovan can also treat left ventricular dysfunction after a heart attack that occurs when the main pumping chamber of the heart stiffens and enlarges and can cause the lungs to fill with blood. Diovan blocks a substance in the body that causes blood vessels to tighten, and relaxes blood vessels.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as Diovan can cause potentially serious complications for both you and your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Diovan without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Tell your doctor immediately if any of the following side effects occur: bloody urine; cold sweats; confusion; decreased frequency/amount of urine; difficult breathing; dizziness, faintness, or lightheadedness when getting up from lying position; fainting; increased blood pressure; increased thirst; irregular heartbeat; loss of appetite; lower back/side pain; nausea; nervousness; numbness or tingling in hands, feet or lips; shortness of breath; swelling of face, fingers, lower legs; troubled breathing; unusual tiredness or weakness; vomiting; weakness or heaviness of legs; weight gain; chills, fever, or sore throat; swelling of face, mouth, hands, or feet; trouble swallowing or breathing; dark urine; general tiredness and weakness; light-colored stools; upper right abdominal pain; or yellow eyes and skin.
Diovan (valsartan) is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT1 receptor subtype. Valsartan is chemically described as N-(1-oxopentyl)-N-[[2' -(1H-tetrazol-5-yl) [1,1'-biphenyl]-4-yl]methyl]-L-valine. Its empirical formula is C24H29N5O3, its molecular weight is 435.5. Diovan is available as tablets for oral administration, containing 40 mg, 80 mg, 160 mg or 320 mg of valsartan. The inactive ingredients of the tablets are colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, iron oxides (yellow, black and/or red), magnesium stearate, microcrystalline cellulose, polyethylene glycol 8000, and titanium dioxide.
Diovan has the following structural formula: