Diltiazem is in a class of drugs called calcium channel/blocker. Diltiazem relaxes your blood vessels which makes it easier for your heart to pump and reduces the workload on it. Diltiazem is used to treat hypertension, to treat angina and to slow unusually fast heartbeat.
Use caution when driving, operating machinery, or performing other hazardous activities. Diltiazem may cause dizziness or drowsiness. Do not open, break or chew any extended-release forms of diltiazem such as Cardizem CD, Cardizem LA, Cardize SR, Cartia XT or Dilacor XR. Swallow them whole.
You may not be able to take diltiazem or you ay require dosage adjustment during treatment if you have any of these conditions: If you have ever had an allergic reaction to any form of diltiazem in the past, kidney disease, liver disease and other disease of heart or blood vessel. Talk to your doctor about consuming grapefruit juice while taking diltiazem. Diltiazem can interact with grapefruit and grapefruit juice and the interaction may have dangerous. Do not take diltiazem without first talking to your doctor if you are pregnant. Diltiazem passes into breast milk and may affect a nursing infant.
Diltiazem is available as tablet and injectable. Take each dose with a full glass of water. If swallowing is difficult, the Tiazac capsules may be opened and the contents sprinkled onto a spoonful of applesauce. The applesauce should be swallowed immediately followed with a glass of water. The applesauce should not be hot and should be soft enough to enable swallowing without chewing. Dilacor XR and Diltia XT should be taken in the morning on an empty stomach. It is important to take diltiazem regularly to get the most benefit. Take diltiazem exactly as directed by your doctor. If you missed a dose of it, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. Store diltiazem at room temperature away from moisture and heat.
Symptoms of diltiazem overdose include dizziness, weakness, chest pain, shortness if breath, fainting, an unusually fast or slow heartbeat, coma, slurred speech and confusion. Seek emergency medical attention if an overdose is suspected.
If you experience any of the following side effects, stop taking diltiazem and contact your doctor immediately or seek emergency medical treatment: An allergic reaction (difficulty breathing, swelling of the lips, tongue or face), hives, unusual fast or slow heartbeat, severe dizziness, psychosis, jaundice, or swelling of the legs or ankles. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Diltiazem hydrochloride is a white to off-white crystalline powder with a bitter taste. It is soluble in water, methanol and chloroform and has a molecular weight of 450.98. Tiazac capsules contain diltiazem hydrochloride in extended release beads at doses of 120, 180, 240, 300, 360 and 420 mg.
Diltiazem has the following structural formula: