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What is the most important information I should know about
rosuvastatin?
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Rare cases of muscle problems and liver problems have been
associated with the use of rosuvastatin and other similar medicines.
Contact your doctor immediately if you experience unexplained muscle
pain, tenderness, or weakness, especially if accompanied by a fever or
flulike symptoms or yellowing of the skin or eyes, abdominal pain,
unexplained fatigue, dark colored urine or pale colored stools. These
may be early symptoms of muscle or liver problems. |
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Rosuvastatin is in the FDA pregnancy category X. This means that
rosuvastatin is known to cause birth defects in an unborn baby when
taken during pregnancy. Do not take rosuvastatin if you are
pregnant or could become pregnant during treatment. |
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Do not take rosuvastatin without first talking to your doctor if you
have liver disease. |
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Rosuvastatin and other similar medicines can cause muscle injury,
which in rare, severe cases, can cause kidney damage and organ failure
that are potentially life-threatening. |
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Alcohol and rosuvastatin can both be damaging to the liver. Discuss
with your doctor the amount of alcohol that you drink so that it can be
determined if rosuvastatin is the best choice for lowering your
cholesterol. |
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Rosuvastatin is an HMG CoA reductase inhibitor. Rosuvastatin blocks
the production of cholesterol (a type of fat) in the body. |
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Rosuvastatin is used to reduce the amounts of LDL (bad) cholesterol,
total cholesterol, triglycerides (another type of fat), and
apolipoprotein B (a protein needed to make cholesterol) in the blood.
Rosuvastatin also increases the level of HDL (good) cholesterol in the
blood. These actions are important in reducing the risk of
atherosclerosis (fatty deposits in the arteries), which can lead to
heart attack, stroke, and peripheral vascular disease. |
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Rosuvastatin may also be used for purposes other than those listed
in this medication guide. |
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What should I discuss with my healthcare provider before taking
rosuvastatin?
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Do not take rosuvastatin without first talking to your doctor if you
have liver disease. |
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Before taking rosuvastatin, tell your doctor if you |
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have hypothyroidism (low thyroid function); |
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drink alcoholic beverages; |
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have a chronic muscular disease; |
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require major surgery; or |
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You may not be able to take rosuvastatin, or you may require a
dosage adjustment or special monitoring during treatment if you have any
of the conditions listed above. |
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• |
Rosuvastatin and other similar medicines can cause muscle injury,
which in rare, severe cases, can cause kidney damage and organ failure
that are potentially life-threatening. |
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• |
Rosuvastatin is in the FDA pregnancy category X. This means that
rosuvastatin is known to cause birth defects in an unborn baby when
taken during pregnancy. Do not take rosuvastatin if you are
pregnant or could become pregnant during treatment. |
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It is not known whether rosuvastatin passes into breast milk and if
it will be harmful to a nursing baby. Do not take this medication
without first talking to your doctor if you are breast-feeding a baby. |
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How should I take rosuvastatin?
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Take rosuvastatin exactly as directed by your doctor. If you do not
understand these directions, ask your pharmacist, nurse, or doctor to
explain them to you. |
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Take each dose with a full glass of water. |
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Rosuvastatin can be taken with or without food. |
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Rosuvastatin is usually taken once a day. Try to take each dose at
the same time daily. Follow your doctor's instructions. |
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It is important to take rosuvastatin regularly to get the most
benefit. Do not stop taking rosuvastatin without first talking to your
doctor. It may be weeks or months before beneficial effects are seen
from this medication. |
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Your doctor may want to monitor your liver function with blood tests
before starting treatment with rosuvastatin, at twelve weeks after start
of treatment and after any increase in dose, and periodically (every 6
months) thereafter. Depending on the results of these tests, your doctor
can determine how much monitoring you will require. |
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Eat a low-fat, low-cholesterol diet. To realize beneficial effects
from rosuvastatin, avoid fatty, high-cholesterol foods. |
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Store rosuvastatin at room temperature away from moisture and heat. |
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What happens if I miss a dose?
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Take the missed dose as soon as you remember. However, if it is
almost time for the next dose, skip the missed dose and take only the
next regularly scheduled dose. Do not take a double dose of this
medication. |
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What happens if I overdose?
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Seek emergency medical attention if an overdose is suspected. |
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The symptoms of a rosuvastatin overdose are not known. |
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What should I avoid while taking rosuvastatin?
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• |
Alcohol and rosuvastatin can both be damaging to the liver. Discuss
with your doctor the amount of alcohol that you drink so that it can be
determined if rosuvastatin is the best choice for lowering your
cholesterol. |
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Do not take rosuvastatin with antacids that contain aluminum and
magnesium such as Maalox, Mylanta, Gelusil and others. If an antacid
that contains aluminum and magnesium is needed, it should be taken at
least 2 hours following a dose of rosuvastatin. |
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What are the possible side effects of rosuvastatin?
|
|
• |
Rare cases of muscle problems and liver problems have been
associated with the use of rosuvastatin and other similar medicines.
Contact your doctor immediately if you experience unexplained muscle
pain, tenderness, or weakness, especially if accompanied by a fever or
flulike symptoms or yellowing of the skin or eyes, abdominal pain,
unexplained fatigue, dark colored urine or pale colored stools. These
may be early symptoms of muscle or liver problems. |
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If you experience a rare but serious allergic reaction (difficulty
breathing; closing of the throat; swelling of the lips, tongue, or face;
or hives) stop taking rosuvastatin and seek emergency medical attention
or contact your doctor immediately. |
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Other, less serious side effects may be more likely to occur.
Continue to take rosuvastatin and talk to your doctor if you experience |
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diarrhea or constipation; or |
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nausea or upset stomach. |
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Side effects other than those listed here may also occur. Talk to
your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect rosuvastatin?
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Do not take rosuvastatin with antacids that contain aluminum and
magnesium such as Maalox, Mylanta, Gelusil and others. If an antacid
that contains aluminum and magnesium is needed, it should be taken at
least 2 hours following a dose of rosuvastatin. |
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Before taking rosuvastatin, talk to your doctor if you are taking
any of the following medicines: |
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cyclosporine (Sandimmune, Neoral); |
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clofibrate (Atromid-S); |
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niacin (Nicolar, Nicobid, Nicotinex, others); or |
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You may require a dosage adjustment or special monitoring during
treatment if you are taking any of the medicines listed above. |
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Drugs other than those listed here may also interact with
rosuvastatin. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines, including vitamins, minerals,
and herbal products. |
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Where can I get more information?
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Your pharmacist has additional information about rosuvastatin
written for health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this
medication only for the indication prescribed. |
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Every effort has been made to ensure that the information provided
by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete,
but no guarantee is made to that effect. Drug information contained
herein may be time sensitive. Multum information has been compiled for
use by healthcare practitioners and consumers in the United States and
therefore Multum does not warrant that uses outside of the United States
are appropriate, unless specifically indicated otherwise. Multum's drug
information does not endorse drugs, diagnose patients or recommend
therapy. Multum's drug information is an informational resource designed
to assist licensed healthcare practitioners in caring for their patients
and/ or to serve consumers viewing this service as a supplement to, and
not a substitute for, the expertise, skill, knowledge and judgment of
healthcare practitioners. The absence of a warning for a given drug or
drug combination in no way should be construed to indicate that the drug
or drug combination is safe, effective or appropriate for any given
patient. Multum does not assume any responsibility for any aspect of
healthcare administered with the aid of information Multum provides. The
information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions,
or adverse effects. If you have questions about the drugs you are taking,
check with your doctor, nurse or pharmacist. |
Copyright 1996-2005 Cerner Multum, Inc. Version: 4.01. Revision date: 10/
10/ 05. |
