Cozaar, also called Losartan, is used to treat high blood pressure by blocking a substance in the body that causes blood vessels to tighten. Cozaar is also used to decrease the risk of stroke in patients with high blood pressure and a condition called left ventricular hypertrophy (LVH).
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Cozaar may affect your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
Avoid alcohol when taking this medicine.
It is very important that you take this medicine exactly as your doctor tells you to. If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Tell your doctor immediately if any of the following side effects occur: hoarseness; swelling of face, mouth, hands, or feet; trouble in swallowing or breathing; abdominal pain ; black, tarry stools ; bleeding gums; blood in urine or stools; coma ; confusion ; convulsions ; decreased urine output ; difficult breathing ; fast or irregular heartbeat ; headache ; increased thirst ; irregular heartbeat ; large, flat, blue or purplish patches in the skin; muscle pain or cramps ; nausea or vomiting nervousness numbness or tingling in hands, feet, or lips ; painful knees and ankles; pinpoint red spots on skin; shortness of breath ; swelling of face, ankles, or hands ; unusual bleeding or bruising; unusual tiredness or weakness; upper right abdominal pain; weakness or heaviness of legs; or yellow eyes and skin.
COZAAR (losartan potassium) is an angiotensin II receptor (type AT1) antagonist. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p- (o-1H-tetrazol-5-ylphenyl)benzyl]imidazole- 5-methanol monopotassium salt. COZAAR is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, titanium dioxide, D&C yellow No. 10 aluminum lake and FD&C blue No. 2 aluminum lake. COZAAR 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively.
Cozaar has the following structural formula: