Coumadin, sometimes known as Warfarin, is an anticoagulant used to decrease blood clotting, and reduce the chance of harmful clots forming in the blood vessels. Though Warfarin may be called a blood thinner, it does not actually thin the blood, nor will they disperse clots that already have formed, but they may prevent the clots from becoming larger and causing more serious problems. They are often used as treatment for certain blood vessel, heart, and lung conditions.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as Coumadin may cause birth defects. Also tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
Avoid alcohol when taking this medicine.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and never stop taking Coumadin without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor immediately if any of the following symptoms occur: bleeding from gums when brushing teeth; blood in urine; nosebleeds; pinpoint red spots on skin; unusual bleeding or bruising; unusually heavy bleeding or oozing from cuts or wounds; unusually heavy or unexpected menstrual bleeding; abdominal or stomach pain or swelling; back pain or backaches; black, tarry stools; bleeding in eye; blood in stools; blood in vomit or vomit that looks like coffee grounds; blood in urine; blurred vision; chest pain; confusion; constipation; coughing up blood; severe diarrhea; dizziness or fainting; joint pain, stiffness, or swelling; loss of appetite; continuing nausea and vomiting; nervousness; numbness or tingling of hands, feet, or face; paralysis; shortness of breath; or sudden weakness.
COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting vitamin K-dependent coagulation factors. Chemically, it is 3-( -acetonylbenzyl)-4-hydroxycoumarin and is a racemic mixture of the R- and S-enantiomers. Crystalline warfarin sodium is an isopropanol clathrate. The crystallization of warfarin sodium virtually eliminates trace impurities present in amorphous warfarin. Its empirical formula is C19 H15 NaO4. Crystalline warfarin sodium occurs as a white, odorless, crystalline powder, is discolored by light and is very soluble in water; freely soluble in alcohol; very slightly soluble in chloroform and in ether. COUMADIN for Injection is supplied as a sterile, lyophilized powder, which, after reconstitution with 2.7 mL sterile Water for Injection.
Coumadin has the following structural formula: