Combivent, a combination of Ipratropium and Albuterol is a bronchodilator (medicine that opens up narrowed breathing passages). It is taken by inhalation to help control the symptoms of lung diseases, such as asthma, chronic bronchitis, and emphysema by increasing the flow of air into the lungs.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Combivent without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, and space out your remaining doses for the day regularly. Do NOT double doses.
Tell your doctor as soon as possible if any of the following side effects occur: chest discomfort or pain; fast or irregular heartbeat; shortness of breath or wheezing; skin rash or hives; swelling of the face, lips, eyelids, mouth, or throat
Combivent Inhalation Aerosol is a combination of ipratropium bromide and albuterol sulfate. Ipratropium bromide is an anticholinergic bronchodiiator chemically described as 8- azoniabicyclo[ 3.2.1] octane, 3-(3-hydroxy-1oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, monohydrate (endo, syn)-,(±+): a synthetic quaternary ammonium compound chemically related to afropine. Ipratropium bromide is a white to off-white crystalline substance. freely soluble in water and lower alcohols but insoluble in lipophilic solvents such as ether, chloroform and fluorocarbons. Combivent Inhalation Aerosol contains a microcrystalline suspension of ipratropium bromide and albuterol sulfate in a pressurized metered-dose aerosol unit for oral inhalation administration. The 200 inhalation unit has a net weight of 14.7 grams. Each actuation meters 21 mcg of ipratropium bromide and 120 mcg of albuterol sulfate from the valve and delivers 18 mcg of ipratropium bromide and 103 mcg of albuterol sulfate (equivalent to 90 mcg albuterol base) from the mouthpiece. The excipients are dichlorodifluoromethane, dichlorotetrafluoroethane, and trichloromonofluoromethane as propellants and soya lecithin.
Combivent has the following structural formula: