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Colchicine Colchicine review
Pharmacy and Drugs

     .: Prescription

Colchicine is a medication used to treat gout attacks. Colchicine is a poisonous pale yellow extract from the autumn crocus. In addition to treating gout it is used in plant breeding science. When taking colchicine it is very important to contact your doctor immediately if you experience these side effects, tiredness, weakness, numbness or tingling, bruising, atypical bleeding, fever or a sore throat. These side effects may be precursor to a more serious reaction. Colchicine, when taken for gout, should be stopped as soon as pain is relieved, when the upper limit of the dose has been taken or the first sign of abdominal pain, diarrhea, vomiting, or nausea. The mechanisms which enable colchicine to treat gout are undiscovered. The current theory is that colchicine alters the body’s reaction to increased or deposited uric acid crystals. This altering of response decreases the painful swelling associated with gout. Colchicine can be used to treat other diseases not listed here.

Before taking this medication, make sure your doctor is aware if you have ever had an allergic reaction to colchicine, have kidney disease or trouble, liver disease, a stomach ulcer, or other digestive problems, heart disease, circulation irregularities. If any of these conditions are present, you may not be able to take colchicine, require a modified dose and/or need special health monitoring while taking this medicine.

The US FDA categorizes drugs based on safety for pregnant women. Colchicine is categorized as C. This indicates that this drug may cause harm to an unborn child, but you should discuss all risk factors with your doctor before taking this medication if you are expecting. Colchicine can pass through breast milk to an infant. Do not take colchicine if you are nursing; discuss the safety with the pediatrician and your physician first.

Colchicine must be taken exactly as prescribed by you doctor. If you have any questions about taking this medication contact your pharmacist or doctor’s office. Each dose should be taken with 8 ounces of water. When treating gout, colchicine can be taken one pill up to once every hour until pain is relieved or the maximum dose has been reached or abdominal pain, diarrhea or nausea occurs. To prevent a reoccurring attack, doctors may sometimes prescribe colchicine to be taken every day or several days a week.

Do not ever take more than is prescribed by your doctor to treat a gout attack. Store this medication at room temperature and away from moisture. A missed dose should be taken as soon as it is remembered. If it is almost time for the regularly scheduled dose, do not double the dose, and simply take the regularly scheduled does. An overdose presents with these symptoms: nausea, burning in throat, stomach or skin, difficulty breathing, delirium, seizures, diarrhea, muscle weakness, vomiting or abdominal pain. An overdose of this medication can be fatal.

When taking this medication, make sure you follow your doctor’s recommendations for diet.

Tell your doctor or pharmacist about any drugs you may be taking or considering taking, whether over-the-counter, herbal remedies, vitamins, minerals or prescription drugs. Do not start a new medication while taking colchicine without out first checking with your doctor or pharmacist.

As always, if you need more information, contact your physician or pharmacist regarding this medication.

Colchicine Tablets, USP are oral anti-inflammatory agents supplied in two dosage strengths 0.5 mg (l/120 gr) and 0.6 mg (l/100 gr). The chemical name for colchicine is (S) N-(5,6,7,9-tetrahydro- 1,2,3, IO-tetramethoxy-9-oxobenzo [alpha] heptaien-7-yl) acetamide. 0.5 mg tablet: Calcium carbonate, confectioner’s sugar (contains corn starch), D& C Yellow No. 10, dextrin, stearic acid, sucrose and talc. 0.6 mg tablet: Acacia, corn starch, D& C Yellow No. 10, lactose, stearic acid and talc.

Colchicine has the following structural formula:

Chemical structure of Colchicine
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