Claritin-D, a combination of Loratadine and Pseuoephedrine is an antihistamine, or an H1 Receptor. It is used to treat the nasal congestion (stuffy nose), sneezing, and runny nose caused by colds and hay fever. Claritin works by blocking the effects of a substance called histamine, which is naturally produced by the body.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Tell your doctor immediately if any of the following side effects occur: chest tightness ; feeling of warmth, redness of the face, neck, arms and occasionally, upper chest; large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs; shortness of breath, or difficult or labored breathing.
Let your doctor know if you have bothersome or continuing: back pain; body aches or pain; chills; coughing; difficulty in moving; dizziness; drowsiness; ear congestion; earache; fever; headache; joint pain; loss of voice; muscle aching or cramping; muscle pains or stiffness; nasal congestion; nausea; pain in arms or legs; pain or tenderness around eyes or cheekbones; painful menstrual bleeding; ringing or buzzing in ears; runny or stuffy nose; sneezing; sore throat; stomach upset; swollen joints; unusual feeling of tiredness or weakness; or a viral infection (such as cold and flu).
Loratadine is a long-acting antihistamine having the empirical formula C22H23ClN2O2; the chemical name ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta [1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate.
The molecular weight of loratadine is 382.89. It is a white to off-white powder, not soluble in water, but very soluble in acetone, alcohol, and chloroform.
Pseudoephedrine sulfate is the synthetic salt of one of the naturally occurring dextrorotatory diastereomers of ephedrine and is classified as an indirect sympathomimetic amine. The empirical formula for pseudoephedrine sulfate is (C10H15NO)2•H2SO4; the chemical name is a-[1-(methyl-amino) ethyl]-[S-(R*,R*)]-benzenemethanol sulfate (2:1)(salt).
The molecular weight of pseudoephedrine sulfate is 428.54. It is a white powder, freely soluble in water and methanol and sparingly soluble in chloroform.
Claritin-D has the following structural formula: