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What is the most important information I should know about
cerivastatin?
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Cerivastatin is not commercially available in the United
States. |
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Contact your doctor immediately if you experience unexplained
muscle pain, tenderness, or weakness, especially if it is accompanied by
a fever or flu-like symptoms or yellowing of your skin or eyes. |
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Do not take cerivastatin without first talking to your doctor
if you have liver disease. |
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Alcohol and cerivastatin can both damage your liver. Discuss
with your doctor the amount of alcohol that you drink so that it can be
determined if cerivastatin is the best choice for lowering your
cholesterol. |
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Do not take cerivastatin if you are pregnant, if you are
planning a pregnancy, or if you are breast-feeding a baby. |
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Cerivastatin blocks the production of cholesterol (a type of
fat) in the body. |
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Cerivastatin is used to reduce the amounts of LDL (bad)
cholesterol and total cholesterol in your blood. Cerivastatin also
reduces the amounts of triglycerides (another type of fat) and
apolipoprotein B (a protein needed to make cholesterol) in your blood
and increases the amount of HDL (good) cholesterol in your blood. These
actions are important in reducing the risk of hardening of the arteries,
which can lead to heart attacks, stroke, and peripheral vascular disease. |
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Cerivastatin is not commercially available in the United
States. |
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Cerivastatin may also be used for purposes other than those
listed in this medication guide. |
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Who should not take cerivastatin?
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Do not take cerivastatin without first talking to your
doctor if you have liver disease. |
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Before taking cerivastatin, tell your doctor if you |
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drink alcoholic beverages, |
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have a chronic muscular disease, or |
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have seizures or epilepsy. |
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You may not be able to take cerivastatin, or you may require
a dosage adjustment or special monitoring during treatment if you have
any of the conditions listed above. |
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Cerivastatin is in the FDA pregnancy category X. This means
that cerivastatin will cause birth defects if it is taken during
pregnancy. Cholesterol is very important for the proper development of a
baby. Do not take cerivastatin if you are pregnant or are
planning a pregnancy. |
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Cerivastatin passes into breast milk and can harm a nursing
infant. Do not take cerivastatin if you are breast-feeding a baby. |
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How should I take cerivastatin?
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Take cerivastatin exactly as directed by your doctor. If you
do not understand these directions, ask your pharmacist, nurse, or
doctor to explain them to you. |
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Take each dose with a full glass of water. |
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Eat a low-fat, low-cholesterol diet. To see beneficial
effects from cerivastatin, avoid fatty, high-cholesterol foods. Follow
your doctor's directions. |
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Your doctor may want to monitor your liver function with
blood tests before starting treatment with cerivastatin, at six and
twelve weeks after both the start of your treatment and any increase in
dose, and periodically (every 6 months) thereafter. Depending on the
results of these tests, your doctor can determine how much monitoring
you will require. |
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Grapefruit and grapefruit juice may interact with
cerivastatin. The interaction could lead to potentially dangerous
effects. Discuss the use of grapefruit and grapefruit juice with your
doctor. Do not increase or decrease the amount of grapefruit products in
your diet without first talking to your doctor. |
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Do not stop taking cerivastatin without first talking to
your doctor. It may be weeks or months before beneficial effects from
this medication are seen. |
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Store cerivastatin at room temperature away from moisture
and heat. |
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What happens if I miss a dose?
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Take the missed dose as soon as you remember. However, if it
is almost time for your next dose, skip the missed dose and take only
your next regularly scheduled dose. Do not take a double dose of
cerivastatin. |
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What happens if I overdose?
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Seek emergency medical attention. |
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Symptoms of an overdose of cerivastatin are not known. |
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What should I avoid while taking cerivastatin?
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Alcohol and cerivastatin can both damage your liver. Discuss
with your doctor the amount of alcohol that you drink so that it can be
determined if cerivastatin is the best choice for lowering your
cholesterol. |
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• |
Grapefruit and grapefruit juice may interact with
cerivastatin. The interaction could lead to potentially dangerous
effects. Discuss the use of grapefruit and grapefruit juice with your
doctor. Do not increase or decrease the amount of grapefruit products in
your diet without first talking to your doctor. |
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What are the possible side effects of cerivastatin?
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If you experience any of the following serious side effects,
stop taking cerivastatin and call your doctor immediately: |
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an allergic reaction (difficulty breathing; closing of your
throat; swelling of your lips, tongue, or face; or hives); |
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muscle aches, pain, or weakness; |
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decreased urine or rust-colored urine; |
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yellowing of your skin or eyes. |
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Other, less serious side effects may be more likely to occur.
Continue to take cerivastatin and talk to your doctor if you experience |
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gas, bloating, nausea, stomach upset, heartburn, abdominal
pain, constipation, or diarrhea; |
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Side effects other than those listed here may also occur.
Talk to your doctor about any side effect that seems unusual or that is
especially bothersome. |
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What other drugs will affect cerivastatin?
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Do not take cerivastatin without first talking to your
doctor if you are taking any of the following medicines: |
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cyclosporine (Sandimmune, Neoral); |
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gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate
(Tricor); |
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niacin (Nicolar, Nicobid, Slo-Niacin, others); |
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erythromycin (E-Mycin, E.E.S., Ery-Tab, others) or
clarithromycin (Biaxin); or |
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itraconazole (Sporanox), fluconazole (Diflucan), or
ketoconazole (Nizoral). |
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The medications listed above may interact with cerivastatin
and damage your muscles. Generally, these medicines are not used
together. |
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Drugs other than those listed here may also interact with
cerivastatin. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines. |
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Where can I get more information?
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Your pharmacist has additional information about
cerivastatin written for health professionals that you may read. |
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Remember, keep this and all other medicines out of the reach
of children, never share your medicines with others, and use this
medication only for the indication prescribed. |
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Every effort has been made to ensure that the information
provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and
complete, but no guarantee is made to that effect. Drug information
contained herein may be time sensitive. Multum information has been
compiled for use by healthcare practitioners and consumers in the United
States and therefore Multum does not warrant that uses outside of the
United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/ or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill, knowledge
and judgment of healthcare practitioners. The absence of a warning for a
given drug or drug combination in no way should be construed to indicate
that the drug or drug combination is safe, effective or appropriate for
any given patient. Multum does not assume any responsibility for any
aspect of healthcare administered with the aid of information Multum
provides. The information contained herein is not intended to cover all
possible uses, directions, precautions, warnings, drug interactions,
allergic reactions, or adverse effects. If you have questions about the
drugs you are taking, check with your doctor, nurse or pharmacist. |
Copyright 1996-2004 Cerner Multum, Inc. Version: 7.03. Revision
Date: 1/ 23/ 04. |