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    Cerivastatin
Cerivastatin pills Cerivastatin review
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Pharmacy and Drugs


     .: Prescription

Cerivastatin blocks the production of cholesterol (a type of fat) in the body. It belongs to a class of drugs called HMG-CoA reductase inhibitor also known as the “statins”. Cerivastatin is used to reduce the amounts of low density lipoprotein (LDL) or the bad cholesterol and total cholesterol in your blood. It also reduces the amount of triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood and increases the amount of high density lipoprotein (HDL) or the good cholesterol in your blood. These actions are important in reducing the risk of hardening of the arteries (atherosclerosis) , which can lead to heart attacks, stroke, and peripheral vascular disease. Cerivastatin is not commercially available in the United States.

Who should not take cerivastatin? • Do not take cerivastatin without first talking to your doctor if you have liver disease. • Before taking cerivastatin, tell your doctor if you • drink alcoholic beverages (alcohol and cerivastatin can both damage your liver) • have kidney disease, • have a chronic muscular disease, or • have seizures or epilepsy.

You may not be able to take cerivastatin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Cerivastatin is in the FDA pregnancy category X. This means that cerivastatin will cause birth defects if it is taken during pregnancy. Do not take cerivastatin if you are pregnant or are planning a pregnancy. Cerivastatin passes into breast milk and can harm a nursing infant. Do not take cerivastatin if you are breast-feeding a baby.

Take cerivastatin exactly as directed by your doctor. To see beneficial effects from cerivastatin, avoid fatty, high-cholesterol foods. Your doctor may want to monitor your liver function with blood tests before starting treatment with cerivastatin, at six and twelve weeks after both the start of your treatment and any increase in dose, and periodically (every 6 months) thereafter. Do not stop taking cerivastatin without first talking to your doctor. It may be weeks or months before beneficial effects from this medication are seen.

Symptoms of an overdose of cerivastatin are not known. Grapefruit and grapefruit juice may interact with cerivastatin that could lead to potentially dangerous effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

If you experience any of the following serious side effects, stop taking cerivastatin and call your doctor immediately: • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); muscle aches, pain, or weakness; a fever; "flu-like" symptoms; decreased urine or rust-colored urine; blurred vision; or yellowing of your skin or eyes.

Other, less serious side effects may be more likely to occur which include: • gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea; dizziness; headache; or a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Drug interactions: Do not take cerivastatin without first talking to your doctor if you are taking any of the following medicines: • cyclosporine (Sandimmune, Neoral); • gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate (Tricor); • niacin (Nicolar, Nicobid, Slo-Niacin, others); • erythromycin (E-Mycin, E.E.S., Ery-Tab, others) or clarithromycin (Biaxin); or • itraconazole (Sporanox), fluconazole (Diflucan), or ketoconazole (Nizoral).

The medications listed above may interact with cerivastatin and damage your muscles. Generally, these medicines are not used together. Drugs other than those listed here may also interact with cerivastatin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines

Cerivastatin sodium is sodium [S-[ R*, S’-( E)] -7-[ 4-( 4-b fluorophenyl)- 5-methoxymethyl)- 2,6bis( l-met ylethyl) 3- pyridinyll-3,5-dihydroxy+ heptenoate. The empirical formula for cerivastatin sodium is C26 H 33FN05Na and its molecular weight is 481.5. BAYCOL (cerivastatin sodium tablets) is supplied as tablets containing 0.2 or 0.4 mg of cerivastatin sodium, for oral administration. Active Ingredient: cerivastatin sodium. Inactive Ingredients: mannitol, magnesium stearate, sodium hydroxide, crospovidone, povidone, iron oxide yellow, methylhydroxypropylcellulose, polyethylene glycol, and titanium dioxide.

Cerivastatin has the following structural formula:

Chemical structure of Cerivastatin
Brand name: Baycol

Similar drugs: Lescol :: Simvastatin :: Gemfibrozil

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