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    Celecoxib
Celecoxib capsules Celecoxib review
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Pharmacy and Drugs


     .: Prescription

Relief of the signs and symptoms of osteoarthritis; relief of the signs and symptoms of rheumatoid arthritis in adults; decreasing intestinal polyps in familial adenomatous polyposis (FAP); management of acute pain; treatment of primary dysmenorrhea. Celecoxib is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Celecoxib works by reducing substances that cause inflammation, pain, and fever in the body.

Celecoxib is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib is also used to reduce the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), to treat acute pain, and to treat pain associated with menstruation.

Celecoxib may also be used for purposes other than those listed in this medication guide. Take celecoxib exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Celecoxib can be taken with or without food or milk. Follow your doctor's instructions.

Your doctor may want you to have blood tests or other medical evaluations during treatment with celecoxib to monitor progress and side effects. Store celecoxib at room temperature away from moisture and heat.

Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes; "flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.

If you experience any of the following serious side effects, stop taking celecoxib and seek medical treatment or call your doctor immediately: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); Other, less serious side effects may be more likely to occur. Continue to take celecoxib and talk to your doctor if you experience flatulence or diarrhea; dizziness; headache; or insomnia.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Before taking celecoxib, tell your doctor if you are taking any of the following drugs: aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate- magnesium salicylate (Trilisate, Tricosal, others), and magnesium s alicylate (Doan's, Bayer Select Backache Formula, others); an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen; diuretic (water pill) such as furosemide (Lasix), hydrochlorothiazide (HydroDiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Hygroton, Thalitone), and others; an angiotensin-converting- enzyme inhibitor (ACE inhibitor) such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), and others; a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others; a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others; an anticoagulant (blood thinner) such as warfarin (Coumadin); lithium (Eskalith, Lithobid, others); or fluconazole (Diflucan).

CELEBREX (celecoxib) is chemically designated as 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide and is a diaryl-substituted pyrazole. The empirical formula for celecoxib is C17H14F3N3O2S, and the molecular weight is 381.38. CELEBREX oral capsules contain either 100 mg, 200 mg or 400 mg of celecoxib. The inactive ingredients in CELEBREX capsules include: croscarmellose sodium, edible inks, gelatin, lactose monohydrate, magnesium stearate, povidone, sodium lauryl sulfate and titanium dioxide.

Celecoxib has the following structural formula:

Celecoxib chemical structure
Brand name: Celebrex

Similar drugs: Topiramate :: Vicoprofen :: Morphine

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