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    Bupropion
Bupropion pills Bupropion review
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Pharmacy and Drugs


     .: Prescription

Bupropion is an antidepressant medication. This medicine is used to treat major depressive disorder and seasonal affective disorder. One brand of bupropion, the Zyban is used to help reduce the cravings and other withdrawal effects of those people who are chronic smokers.

Do not take bupropion if you have: epilepsy or a seizure disorder; an eating disorder such as anorexia or bulimia; if you are using a second form of bupropion; or if you have suddenly stopped using alcohol or sedatives (such as Valium); heart disease or high blood pressure; head injury, brain or spinal cord tumor; kidney disease; liver disease (especially cirrhosis); bipolar disorder (manic depression); diabetes for which you use insulin or take oral medication; current use of steroids, theophylline (Theo-Dur, Slo-Bid, Bronkodyl Theolair, Respbid), or medicine to treat depression or mental illness; or , narcotic pain medicines, diet pills, or street drugs such as "speed" or cocaine. If you have any of these conditions, you may not be able to use bupropion, or you may need a dosage adjustment or special tests during treatment.

Bupropion may trigger seizures, especially in people with certain medical conditions or when using certain drugs. If you are below 18 years of age, you may have an increased risk of suicidal thoughts or behavior at the start of treatment with an antidepressant medication. This is the reason why you will need to be monitored for worsening symptoms of depression and/ or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed. Also, your doctor will need to examine you at regular visits for at least the first 12 weeks of treatment.

Inform your doctor if you have any of the following side effects, especially if they are new symptoms or if they get worse: mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania (mental and/ or physical hyperactivity), or suicidal thoughts and hurting yourself. Bupropion may be harmful to an unborn baby and may also pass into breast milk thus, could harm a nursing infant. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is also advisable to tell your doctor if you are breast-feeding.

Do not take bupropion in larger doses or for longer than recommended by your doctor. Unpleasant side effects may appear if you immediately stop this drug so do not stop taking bupropion abruptly without telling your doctor. Do not also take a double dose of this drug if you missed the regularly scheduled dose.

If you are taking Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine but set a date to quit smoking during the second week of Zyban treatment. If you are still having problems in smoking cessation after you have used Zyban for at least 7 weeks then inform your doctor. You may be prescribed with nicotine patches or gum to help support you in quitting smoking. Do not smoke at any time if you are using a nicotine product along with Zyban because it may raise your blood pressure.

Seek emergency medical attention if you think you have taken a lot this medicine. Symptoms of a bupropion overdose may include seizures, muscle stiffness, hallucinations, fainting, fast or uneven heartbeat, shallow breathing, heart failure, or coma.

Avoid alcohol because it may increase your risk of a seizure while you are taking bupropion. If you drink alcohol regularly do not change the amount you drink suddenly without informing your doctor. Bupropion can cause seizures in those people who are regularly drinking alcohol and then suddenly quit drinking when they start taking bupropion. Also avoid using bupropion in treating more than one condition at a time. If you take Wellbutrin for depression, do not also take Zyban to quit smoking. Too much of this medicine can increase your risk of a seizure. Bupropion can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Get emergency medical attention if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Discontinue using bupropion and call your doctor at once if you have a seizure (convulsions) or fast, irregular heartbeats. While you may continue taking bupropion but talk to your doctor if you have any of these less serious side effects: headache or migraine; sleep problems (insomnia); nausea, vomiting, constipation, dry mouth; confusion, dizziness, agitation, tremors (shaking); appetite changes, weight loss or gain; mild itching or skin rash, increased sweating; or loss of interest in sex. Talk to your doctor about any other unusual side effect.

Do not take bupropion if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl), or tranylcypromine (Parnate) in the last 14 days. Other drugs not listed here are may affect bupropion. Tell your doctor about all the prescription and over-the-counter medications you use including vitamins, minerals, herbal products, and drugs prescribed by other doctors.

WELLBUTRIN is supplied for oral administration as 75-mg (yellow-gold) and 100-mg (red) film-coated tablets. Each tablet contains the labeled amount of bupropion hydrochloride and the inactive ingredients: 75-mg tablet – D&C Yellow No. 10 Lake, FD&C Yellow No. 6 Lake, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, talc, and titanium dioxide; 100-mg tablet – FD&C Red No. 40 Lake, FD&C Yellow No. 6 Lake, hydroxypropyl cellulose, hypromellose, microcrystalline cellulose, polyethylene glycol, talc, and titanium dioxide.

Bupropion has the following structural formula:

Chemical structure of Bupropion
Brand name: Wellbutrin :: Wellbutrin SR :: Wellbutrin XL :: Zyban

Similar drugs: Zyprexa :: Methadone :: Phenergan

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