Avapro, or Irbesartan, belongs to a class of medicines called Angiotensin II Inhibitor Antihypertensives. It is used to treat high blood pressure. Avapro works by relaxing blood vessels by blocking the action of a substance in the body that causes blood vessels to tighten.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as it is unknown how Avapro may affect your baby. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Avapro without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor as soon as possible if any of the following side effects occur: dizziness, lightheadedness, or fainting; confusion, irregular heartbeat, numbness or tingling in hands, feet, or lips, shortness of breath, difficult breathing , or weakness or heaviness of legs; clay-colored stools, dark urine, itching, loss of appetite, stomach pain, or yellow eyes or skin; or large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet or sex organs.
AVAPRO (irbesartan) is an angiotensin II receptor (AT1 subtype) antagonist.
Irbesartan is a non-peptide compound, chemically described as a 2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl) benzyl]-1,3-diazaspiro[4,4]non-1-en-4-one.
AVAPRO is available for oral administration in unscored tablets containing 75 mg,150 mg,or 300 mg of irbesartan. Inactive ingredients include: lactose, microcrystalline cellulose, pregela-tinized starch, croscarmellose sodium, poloxamer 188,silicon dioxide and magnesium stearate.
Its empirical formula is C25H28N6O,and the structural formula: