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    Avandia
Avandia tablets Avandia review
by
Pharmacy and Drugs


     .: Prescription

Also called Rosiglitazone, Avandia is used to treat Type 2 Diabetes. It may be used alone or with another type of diabetes medicine.

Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.

It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Avandia without discussing it with your doctor first.

If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.

Tell your doctor as soon as possible if any of the following side effects occur: abdominal or stomach pain; blurred vision; chest pain or discomfort; decrease in amount of urine; dry mouth; fatigue; flushed, dry skin; fruit-like breath odor; increased hunger; increased thirst; increased urination; irregular heartbeat; nausea; noisy, rattling breathing; pain in the shoulders, arms, jaw or neck; shortness of breath; sweating; swelling of fingers, hands, feet, or lower legs; troubled breathing; unexplained weight loss; weight gain, rapid or unusual; or vomiting.

AVANDIA (rosiglitazone maleate) is an oral antidiabetic agent which acts primarily by increasing insulin sensitivity. AVANDIA is used in the management of type 2 diabetes mellitus (also known as non-insulin-dependent diabetes mellitus [NIDDM] or adult-onset diabetes). AVANDIA improves glycemic control while reducing circulating insulin levels. Pharmacological studies in animal models indicate that rosiglitazone improves sensitivity to insulin in muscle and adipose tissue and inhibits hepatic gluconeogenesis. Rosiglitazone maleate is not chemically or functionally related to the sulfonylureas, the biguanides, or the alpha-glucosidase inhibitors. Chemically, rosiglitazone maleate is (±)-5-[[4-[2- (methyl-2-pyridinylamino) ethoxy] phenyl]methyl] -2,4-thiazolidinedione, (Z)-2-butenedioate (1:1) with a molecular weight of 473.52 (357.44 free base). The molecule has a single chiral center and is present as a racemate. Due to rapid interconversion, the enantiomers are functionally indistinguishable. Each pentagonal film-coated TILTAB ® tablet contains rosiglitazone maleate equivalent to rosiglitazone, 2 mg, 4 mg, or 8 mg, for oral administration. Inactive ingredients are: Hypromellose 2910, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3000, sodium starch glycolate, titanium dioxide, triacetin, and 1 or more of the following: Synthetic red and yellow iron oxides and talc.

The structural formula of rosiglitazone maleate is:

Avandia chemical 
structure


Generic name: Rosiglitazone

Brand name(s):

Similar drugs: Metformin :: Actos :: Glipizide

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