Avandamet, a combination of Rosiglitazone and Metformin, is used to treat high blood sugar that is caused by Type 2 Diabetes. Rosiglitazone helps your body use insulin better and it reduces the actual amount of insulin in your body. Metformin reduces the absorption of sugar, reduces the release of stored sugar from the liver, and helps your body's cells use the sugar in your body better.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and don’t stop taking Avandamet without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Call your doctor immediately if any of the following side effects occur: pale skin; troubled breathing with exertion; unusual bleeding or bruising; unusual tiredness or weakness; anxiety; blurred vision; chest pain or discomfort; chills; cold sweats; coma; confusion; cool pale skin; depression; dilated neck veins; dizziness; extreme fatigue; fast heartbeat; headache; increased hunger; irregular breathing; irregular heartbeat; nausea; nervousness; nightmares; seizures; shakiness; shortness of breath; slurred speech; swelling of face, fingers, feet, or lower legs; weight gain; or wheezing.
AVANDAMET is available for oral administration as tablets containing rosiglitazone maleate and metformin hydrochloride equivalent to: 1 mg rosiglitazone with 500 mg metformin hydrochloride (1 mg/500 mg), 2 mg rosiglitazone with 500 mg metformin hydrochloride (2 mg/500 mg), 4 mg rosiglitazone with 500 mg metformin hydrochloride (4 mg/500 mg), 2 mg rosiglitazone with 1,000 mg metformin hydrochloride (2 mg/1,000 mg), and 4 mg rosiglitazone with 1,000 mg metformin hydrochloride (4 mg/1,000 mg). In addition, each tablet contains the following inactive ingredients: Hypromellose 2910, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol 400, povidone 29-32, sodium starch glycolate, titanium dioxide, and 1 or more of the following: Red and yellow iron oxides.
The structural formula is:
Generic name: Metformin and rosiglitazone
Similar drugs: Microzide