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    Aripiprazole
Aripiprazole tablets Aripiprazole review
by
Pharmacy and Drugs


     .: Prescription

Aripiprazole is an antipsychotic medication, indicated in the treatment of schizophrenia, acute and mixed episodes associated with bipolar disorder (manic depression), and maintenance therapy for bipolar I disorder. It works by changing the actions of chemicals in the brain.

Special precautions: Dementia-related psychosis and cardiovascular adverse events in elderly. Aripiprazole has caused fatal heart attack and stroke in older adults with dementia-related conditions. Neuroleptic malignant syndrome, tardive dyskinesia, hyperglycemia, diabetes mellitus, orthostatic hypotension, seizure, dysphagia (difficulty in swallowing). Potential for cognitive and motor impairment so do not drive or do anything that requires you to be fully awake and alert. Do not take other medicines that will make you sleepy such as cold medicine, analgesics, muscle relaxants and medicine for seizures, depression or anxiety. Renal and hepatic impairment, pregnancy and lactation and children. Avoid overheating and dehydration so drink plenty of fluids especially while exercising and during summer.

Stop using aripiprazole at once when you experience the following adverse reactions: Rigidity, tachycardia (rapid heart rate), hypotension, bradycardia (slowness of heart beat), headache, nausea, dyspepsia, vomiting, constipation, agitation, anxiety, insomnia, somnolence, akathisia, lightheadedness, hypothyroidism, skin reactions, urinary incontinence, uncontrolled muscle movements, sudden onset of numbness or weakness, severe headache and visual, speech or balance impairment.

Before taking aripiprazole, inform your doctor if you have the following conditions: liver disease, kidney, heart disease, high blood pressure, irregular rhythm problems, a previous history of heart attack or stroke (brain attack), a history of breast cancer, seizures or epilepsy, a personal or family history of diabetes and difficulty in swallowing. If you have any of the above conditions, either you are not able to take aripiprazole or may need some dosage adjustment and special tests for monitoring of drug levels in the blood during treatment.

To be able to get the most benefit, it is important to take aripiprazole regularly. You also need to follow up regularly to your doctor to be sure this medication is helping your condition. Get emergency help if you have the allergic reactions such as wheals (hives), difficulty of breathing, facial swelling, lips, tongue or throat.

Drug interactions: carbamazepine (Tegretol), Phenobarbital (Luminal, Solfoton) or phenytoin; rifabutin (Mycobutin) or rifampicin (Rifadin, Rimactane, Rifater), ketoconazole (Nizoral), itraconazole (Sporanox), quinidine (Cardioquin, Quinaglute), fluoxetine (Prozac), fluvoxamine (Luvox) or paroxetine (Paxil). To be safe, tell your doctor for any prescription and over-the-counter medications that you use while taking aripiprazole.

Aripiprazole is a psychotropic drug that is available as ABILIFY (aripiprazole) tablets, ABILIFY DISCMELT (aripiprazole) orally disintegrating tablets, and in solution for oral administration. Aripiprazole is 7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydrocarbostyril. The empirical formula is C23H27Cl2N3O2 and its molecular weight is 448.39. ABILIFY tablets are available in 2-mg, 5-mg, 10-mg, 15-mg, 20-mg, and 30-mg strengths. Inactive ingredients include cornstarch, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate and microcrystalline cellulose. Colorants include ferric oxide (yellow or red) and FD&C Blue No. 2 Aluminum Lake. ABILIFY DISCMELT orally disintegrating tablets are available in 10-mg, 15-mg, 20-mg, and 30-mg strengths. Inactive ingredients include acesulfame potassium, aspartame, calcium silicate, croscarmellose sodium, crospovidone, crème de vanilla (natural and artificial flavors), magnesium stearate, microcrystalline cellulose, silicon dioxide, tartaric acid, and xylitol. Colorants include ferric oxide (yellow or red) and FD&C Blue No. 2 Aluminum Lake.

Aripiprazole has the following structural formula:

Aripiprazole chemical structure
Brand name: Abilify :: Abilify Discmelt

Similar drugs: Tysabri :: Lexapro :: Verapamil

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